Application Gallery

The Application Gallery features COMSOL Multiphysics tutorial and demo app files pertinent to the electrical, mechanical, fluid, and chemical disciplines. You can download ready-to-use tutorial models and demo apps with step-by-step instructions for how to create them yourself. The examples in the gallery serve as a great starting point for your own simulation work.
Use the Quick Search to find tutorials and apps relevant to your area of expertise. Log in or create a COMSOL Access account that is associated with a valid COMSOL license to download the MPH-files.

Liquid Chromatography

In the simplest terms, High Performance Liquid Chromatography (HPLC) is a separation technology - a process used to separate different chemical species that are in a mixture. And while HPLC is one of many separation technologies available, it is the most prevalent because of its versatility. These systems are most commonly used in the pharmaceutical and biotech industries, in functions as ...

Electrophoresis, Transport in a Capillary Column

The electrophoresis of a mixture containing benzoic acid and chlorobenzoic acid, with sodium acetate as background electrolyte, is studied in a model that includes the transport of the involved species through diffusion and migration. The transport equations are combined with the material balances and the electroneutrality condition. The neutralization reaction for all the involved acid-base ...

Drug Release from a Biomaterial Matrix

In this example, drug-release from a biomaterial matrix to damaged cell tissue is modeled. Specifically, a nerve guide delivers a regenerating drug to damaged nerve ends. The model involves detailed drug release kinetics, with rate expressions handling drug dissociation/association reactions as well as matrix degradation by enzyme catalysis. The enzyme reaction is described by Michaelis-Menten ...

Cylindrical Catalyst Pellet

Porous catalyst particles are widely used in the chemical industry and are extensively treated in the chemical engineering literature. The catalyst pellets are, in most cases, fluidized by the action of a gas or liquid flowing through a reactor. The fluid enters at the bottom of a bed of catalyst particles and the particles are fluidized by the shear force that the fluid exerts on their ...

Degradation of DNA in Plasma

Biotechnology is a rapidly growing area in the pharmaceutical sciences. One example of a clinical application is gene therapy, where it is possible to produce proteins in vivo, using the body’s own mechanisms for protein production. Major issues in gene delivery involve the transport of plasmid DNA (pDNA) to target sites and the conversion between different forms of pDNA. This model ...

Diffusion of Gas Through a Reinforced 3D Membrane

In this example, we study the diffusion of a chemical species through a membrane. The system is used to measure the permeability of gases in membranes. The permeability of the membrane is measured by introducing the species of interest in a carrier gas on one side of the membrane and the pure carrier gas on the other side of the membrane. In this model, the initial flux in the membrane is ...

Optimal Cooling of a Tubular Reactor

Maximizing product yield is a main task in chemical reaction engineering. This can be especially challenging if the desired product, once formed, can be consumed by further reactions. This example investigates such a series reaction as it occurs in a tubular reactor. You will start by setting up the tightly coupled mass and energy balance equations describing the reactor using predefined ...

Hydrocarbon Dehalogenation in a Tortuous Microreactor

Removing halogen groups from hydrocarbons is an important reaction step in several chemical processes. One application is water purification. Other examples involve organic synthesis, where the removal of halogen groups serves as a starting point for carbon-carbon coupling reactions. Typically, the carbon-halogen bond scission is activated by precious metal catalysts based on platinum or ...

Tank Series with Feedback Control

This example illustrates how to set up and solve a tank-in-series model in 0D using the Reaction Engineering interface. The model treats a series of three consecutive tank reactors. A feedback loop continuously adjusts the inlet concentration of the first tank in order to keep the concentration at the outlet of the last reactor close to a set level.

Monolithic Reactor

This model simulates the catalytic abatement of a volatile organic compound (VOC), in this case a contaminant in a waste gas. An analytical expression describes the velocity profile in the free channel, while reaction occurs in the washcoat that makes up the tubular shape of the free channel. For simple geometries, the reactor can be described by a 2D model using time as the axial direction ...

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