Model Gallery

The Model Gallery features COMSOL Multiphysics model files from a wide variety of application areas including the electrical, mechanical, fluid, and chemical disciplines. You can download ready-to-use models and step-by-step instructions for building the model, and use these as a starting point for your own modeling work. Use the Quick Search to find models relevant to your area of expertise, and login or create a COMSOL Access account that is associated with a valid COMSOL license to download the model files.

Degradation of DNA in Plasma - new

Biotechnology is a rapidly growing area in the pharmaceutical sciences. One example of a clinical application is gene therapy, where it is possible to produce proteins in vivo, using the body’s own mechanisms for protein production. Major issues in gene delivery involve the transport of plasmid DNA (pDNA) to target sites and the conversion between different forms of pDNA. This model ...

Chemical Equilibrium in a Protein Adsorption Ion-exchanger

This example uses algebraic equilibrium relations to model the time-dependent adsorption of proteins to an ion-exchange medium. The fluid phase contains three components: two proteins and one salt. The adsorption/desorption kinetics are described by a set of equilibrium reactions where proteins displace ions adsorbed at the surface and vice versa. The model highlights the implementation of ...

Stefan Tube

This example shows 1D steady-state multicomponent gas diffusion. The diffusion of three gases in a Stefan tube is modeled in 1D. The steady-state mass fraction profiles are calculated. It exemplfies in a simple way manipulation of multi-species diffusion. It also shows how this can influence convective movement. The model is compared to an article with experimental results.

Liquid Chromatography

In the simplest terms, High Performance Liquid Chromatography (HPLC) is a separation technology - a process used to separate different chemical species that are in a mixture. And while HPLC is one of many separation technologies available, it is the most prevalent because of its versatility. These systems are most commonly used in the pharmaceutical and biotech industries, in functions as ...

Isoelectric Separation

This modeling example applies the Transport of Diluted Species interface to model a separation process. A stream containing six different ionic species is divided into pure component streams by means of migrative transport in an electric field. Free flow electrophoresis can be used to separate macromolecules such as proteins, based on their mobility perpendicular to the flow of the carrier fluid. ...

Maxwell-Stefan Diffusion in a Fuel Cell Unit Cell

In concentrated gases and liquids, where the concentrations of species are of the same order of magnitude, there is no obvious solvent-solute relationship. Fick’s law for diffusion accounts only for one-way solute-solvent interactions whereas the Maxwell-Stefan equations account for all interactions of species in a solution. In a system with three components, three pair-wise interactions are ...

Isothermal HI Reactor

For a perfectly mixed reactor with a predefined constant temperature, the reacting system’s energy balance is not needed to describe the system behavior. The behavior is defined as the composition and the production or consumption of species over time. Furthermore, because the reactor is perfectly mixed, the Reaction Engineering interface can also set up a model even though it has no ...

Fine Chemical Production in a Plate Reactor

Plate reactors running under continuous conditions have emerged as candidates to replace batch reactors, primarily in fine chemicals and pharmaceuticals production. One of the advantages of the plate reactor design is that it allows for efficient temperature control of the reacting fluid. For instance, this means that the heat released from strongly exothermic reactions can be readily dissipated ...

Tank Series with Feedback Control - new

This example illustrates how to set up and solve a tank-in-series model in 0D using the Reaction Engineering interface. The model treats a series of three consecutive tank reactors. A feedback loop continuously adjusts the inlet concentration of the first tank in order to keep the concentration at the outlet of the last reactor close to a set level.

Polymerization in a Semibatch Reactor

As reactant monomer converts into polymer chains, the density of the reacting mixture often changes notably. In this example you will look at how this effect impacts the total production of polymer in a process. The liquid phase polymerization takes place in a semibatch reactor, where two operating conditions are compared. In the first scenario, the feed of monomer to the reactor is turned off ...

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