Design of a High Field Gradient Electromagnet for Magnetic Drug Delivery to a Mouse Brain

I. Hoke, C. Dahmani, T. Weyh

Heinz-Nixdorf Lehrstuhl für Medizinische Elektronik, Fakultät für Elektro-und Informationstechnik, Technische Universität München, Germany

The application of nanoparticles coupled with medical agents to brain tumors remains one of the biggest obstacles in neuro scientific research. This work explores an optimal design of an electromagnet to overcome the blood-brain barrier by means of an intensive external magnetic field gradient. It is found that the field gradients depend strongly on the design of the magnet tip. The model consists of an optimized coil and magnet system to focally target the brain of a small animal. Computations concerning the heating of the coil are presented as well as its simulation using COMSOL Multiphysics.

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