Designing an Array of Nanocalorimeters for Screening Biochemical Interactions

F. Torres
Palo Alto Research Center

In this presentation we present our analysis of the PARC Nanocalorimeter.

Calorimetry is basically the measuring of heat of chemical reactions or physical changes. Nanocalorimetry is Calorimetry at the Nanometer scale. The PARC Nanocalorimeter is a special type of Calorimeter, it consists of arrays of Nanocalorimeters. The PARC Nanocalorimeter is intended to be used for screening biochemical reactions in drug discovery.

In the present work, we present the basics of Nanocalorimeters, numerical modeling of Nanocalorimeters, and how to perform Design Calculations.

Keynote speaker's biography: Frank Torres works at the Palo Alto Research Center (PARC) on inventing and delivering novel biotechnologies. Life sciences research is relatively new for PARC, but PARC has already made significant investments in this area and developed strong collaborations, among them being the Scripps-PARC Institute for Advanced Biomedical Sciences, a partnership with The Scripps Research Institute (TSRI).

Prior to beginning his research in the life sciences, Frank was involved in forming and spinning out Gyricon Media Incorporated (GMI), a company chartered with commercializing Gyricon electronic paper invented at PARC. He managed the media development group for GMI, with responsibilities including both internal activities and a joint development effort with 3M. Previously, he performed research and scale-up engineering on novel toner processes at the Xerox Research Centre of Canada, collaborating with Xerox U.S. and Fuji-Xerox.

Frank was a postdoctoral research fellow at Exxon Research & Engineering Company prior to joining Xerox. He received his Ph.D. in Chemical Engineering from Princeton University, studying under Professors William Russel and William Schowalter, and he received his B.S. in Chemical Engineering from the University of California at Davis. Frank lives with his wonderful wife and children in San Jose, CA.

F. Torres was one of the keynote speakers at the COMSOL User's Conference, fall 2006 in Las Vegas.