Mathematical Modeling of Atheroma Plaque Deformation using COMSOL Multiphysics

N. El Khatib1, S. Genieys1, M. Zine2, and V. Volpert1
1Institut Camille Jordan, Université Claude Bernard, Lyon, France
2Département Maths & Informatique, Ecole Centrale de Lyon, Lyon, France

The development of atherosclerosis leads to the formation of an atheroma plaque which takes place in the artery. This plaque is composed of two parts: a lipid deposit and a fibrous cap. The fibrous cap covers the lipid deposit and isolates it from the blood flow.

The blood flow that circulates in the artery modifies the geometry of the atheroma plaque and can cause dangerous effects, such as a rupture of the plaque and the liberation of solid parts which can block the blood circulation.

The problem is modeled as a fluid-structure interaction between the blood and the plaque where the simulations are done with COMSOL Multiphysics.