J. Rasmussen, M.S. Enevoldsen, J. Thyregod, and K-A. Henneberg
Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark
COOK Medical Europe, Bjaeverskov, Denmark
This work presents new Fluid-Structure Interaction (FSI) models in both 2D and 3D of the effect of using vascular stents as treatment of cerebral berry aneurysms. The stent is positioned inside the cerebral artery covering the neck of the aneurysm. The stent is expected to alter the blood flow into the aneurysm such that the blood coagulates due to low blood velocity, and rupture of the aneurysm ...
E. Engström, B. Balfors, and R. Thunvik
Royal Institute of Technology, Stockholm, Sweden
In this study we evaluate transport, retention and subsistence of Escherichia coli (E. coli), a common fecal indicator bacteria, in a model (2x1m) of a constructed wetland. Transport occurs in the unsaturated and saturated zone. Inactivation is accounted for as a kinetic first-order process. Retention is assumed to be dominated by solid-air-water interface straining and is modeled with a kinetic ...
A. Avanzini, D. Battini, M. Berardi
Università degli Studi di Brescia, Brescia, Italy
The complex behavior of biological prosthetic heart valves was simulated. A multiphysics computational approach was adopted using different modules of COMSOL Multiphysics: the LiveLink(TM) interface was used to exchange the valve geometry with CAD, Structural Mechanics Module to set loads, boundary conditions and implement anisotropic hyper-elastic constitutive laws for leaflet tissue, PDE to ...
A. Sun, and S. Murray
Dept. of Biomedical Engineering
UCLA, Los Angeles, CA
Implantable Collagen sponges are used in Spinal Surgery as Drug Delivery Scaffolds. An optimal concentration of growth factor that strikes a balance between bone growth and adverse diffusion effects is difficult to find. The porous sponge also serves as a scaffold for Osteoblast growth, and fluid shear has been shown to mediate biological effects on that cell type. We use COMSOL Multiphysics ...
Image-based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-pulmonary Applications
A. Harkara, R.M. Heethaar, R.T. Cotton, and F.K. Hermans
Simpleware Ltd., Exeter, UK
VU University Medical Center, Amsterdam, Netherlands
For medical diagnostic purposes there is an increasing need for non-(or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the heart and Electric Impedance Tomography (EIT) is used for investigating lung tissue condition. The PDE is ...
Compensating Spatial Variability of Quantity Index in 2D Electrical Impedance Tomography: COMSOL Multiphysics Study
S. Oh, and R. Sadleir
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
In Electrical Impedance Tomography (EIT), an array of surface electrodes is used to inject current and measure the resulting voltages to non-invasively obtain conductivity distributions of objects. The system can be easily implemented as a device that monitors hemorrhage, respiration, gastric emptying or brain activities.The Quantity Index (QI), an integral measure of reconstructed images, can be ...
H. Esfandyarpour1,2, A. Maiyegun1, and R. W. Davis2
1Center for Integrated Systems, Department of Electrical Engineering, Stanford University, Stanford, CA, USA
2Stanford Genome Technology Center, Stanford, CA, USA
We present a preliminary investigation of a Nanoneedle biosensor as an ultra sensitive and localized impedance biosensor using COMSOL.This preliminary study was performed to prove the feasibility of the impedance biosensor for detection of protein or nucleic acids. By monitoring the change in capacitance and impedance of this structure, we aim to characterize and classify biological species such ...
C. Gavrila, A. Ghiaus, and I. Gruia
Technical University of Civil Engineering Bucharest, Faculty of Building Services, Bucharest, Romania
University of Bucharest, Faculty of Physics, Bucharest, Romania
A dynamic mathematical model, based on physical and transport properties and mass and energy balances, was developed for the simulation of unsteady convective drying of agricultural products (fruits and vegetables) in static bed conditions. The model utilizes water sorption isotherm equations and the change in solid density due to the shrinkage phenomenon. The aim of this article is to describe ...
T. Selvam, V.P. Kotte, and M. Marimuthu
HCL Technologies Ltd, Chennai, Tamil Nadu, India
Globally in Otolaryngology industry, Sinusitis is one of the most common diseases related to the nose. Sinusitis is caused when the cilia fail to move the mucus. As a result sinus tissue gets infected that leads to blockage of the sinuses. All the sinusitis can not be cured through drugs and certain require surgery. When a sinus cavity subjected to a nasal endoscopic surgical procedure, one of ...
Numerical Investigation of a Time-dependent Magnetic Actuation Technique for Tagging Biomolecules with Magnetic Nanoparticles in a Microfluidic System
A. Munir, J. Wang, Z. Zhu, and H.S. Zhou
Worcester Polytechnic Institute, Worcester, MA, USA
The magnetic body forces that act on mono-dispersed magnetic nanoparticles (MNPs) tagged biomolecules in a microfluidic system can be efficiently used in various applications that involve separation and detection including DNA and protein analysis, bio-defense, drug delivery, and pharmaceutical development. In this work, we report an FEM model to demonstrate a novel method of tagging biomolecules ...