Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Rapid Prototyping of Biosensing Surface Plasmon Resonance Devices using COMSOL & Matlab software

J.J. Dubowski[1], and D.Carrier[1]
[1]Department of Electrical and Computer Engineering, Université de Sherbrooke, Quebec, Canada

We present a Finite Element Method simulation procedure that allows rapid development of prototype devices comprising novel self-referenced interference SPR (surface plasmon resonance) biosensing microstructures. The procedure takes advantage of  COMSOL Multiphysics and MATLAB software and their bi-directional link. The simulation is made using COMSOL RF Module, 2D harmonic propagation ...

3D Modeling of Impedance Spectroscopy for Protein Detection in Nanoneedle Biosensors

H. Esfandyarpour1,2, A. Maiyegun1, and R. W. Davis2
1Center for Integrated Systems, Department of Electrical Engineering, Stanford University, Stanford, CA, USA
2Stanford Genome Technology Center, Stanford, CA, USA

We present a preliminary investigation of a Nanoneedle biosensor as an ultra sensitive and localized impedance biosensor using COMSOL.This preliminary study was performed to prove the feasibility of the impedance biosensor for detection of protein or nucleic acids. By monitoring the change in capacitance and impedance of this structure, we aim to characterize and classify biological species such ...

Computational Modeling and Simulation of the Human Duodenum

B. Hari[1], S. Bakalis[1], P. Fryer[1]
[1]The University of Birmingham, School of Chemical Engineering, Edgbaston, Birmingham, United Kingdom

Worldwide attention in the computational modeling and simulation of the human intestine is increasing in order to help understand its complex behavior and improve health. Computational fluid dynamics is an essential tool to understand the mechanics and transport phenomena of the human intestine, thereby advancing the diagnosis and treatment of gastrointestinal related diseases. The aim of this ...

Improving Detection Sensitivity for Nanoscale Targets Through Combined Photonic and Plasmonic Techniques

G. Zhang[1], Y. Zhao[1]
[1]Clemson University, Clemson, SC, USA

Photonic technique such as the whispering gallery mode (WGM) is often used for detection of small particles like bacteria and viruses. It offers good detection sensitivity and is advantageous over other detection techniques because the detection can be label free. However, the detection sensitivity may not be sufficient when the size of the detection target is in nanoscale. To change this, we use ...

Acoustic Field Comparison of High Intensity Focused Ultrasound Using Experimental Characterization and Finite Element Simulation

J. L. Teja[1], A. Vera[1], L. Leija[1]
[1]Department of Electrical Engineering, Cinvestav-IPN, Mexico D.F., Mexico

High Intensity Focused Ultrasound (HIFU) is used as a noninvasive technique of tissue heating and ablation for different medical treatments. This paper presents a quantitative comparison of HIFU acoustic fields experimentally obtained versus simulated acoustic fields. Acoustic field characterization was realized in two HIFU transducers using water as a propagation medium. Also, simulations were ...

Heat Transfer and Phase Transformation on Matrix Assisted Pulsed Laser Evaporation (MAPLE) of Biocompatible Thin Layers

E. Lacatus[1], G.C. Alecu[1], M.A. Sopronyi[2], A. Tudor[1]
[1]POLITEHNICA University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

Matrix Assisted Pulsed Laser Evaporation (MAPLE) technique is used for the deposition of high quality biocompatible polymer thin films. During the deposition process the temperature of the laser target should be kept below 193K to assure the proper quality of both evaporation and deposition phases of the process. On a first approach COMSOL Multiphysics® was used to describe and analyze the ...

Analysis of 3D Biocompatible Additive Structure Using COMSOL Multiphysics® Software - new

E. Lacatus[1], M. A. Sopronyi[2], G. C. Alecu[1], A. Tudor[1]
[1]Polytechnic University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

For biocompatible prosthetics, from dental implants up to bone parts, manufacturers have to find the best way to correlate process parameters and the material properties as to meet the unique needs of individuals. Additive manufacturing techniques aim at creating complex biocompatible structures able to overcome the present shortfalls of the metal and metal alloys implants related to ...

Coupled Electromagnetics-Multiphase Porous Media Model for Microwave Combination Heating

V. Rakesh, and A. Datta
Dept. of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA

Although microwave heating has been studied in great detail, microwave combination heating has not. This work investigated this in a novel microwave combination system that heats the sample through a combination of microwaves and hot air. The study used a coupled electromagnetics-multiphase porous media model in COMSOL to determine the effect of combining different heating modes on heating ...

Model of an Interdigitated Electrodes System for Cell Counting Based on Impedance Spectroscopy

E. Bianchi[1][2], F. Bellati[1], E. Rollo[2], G. Dubini[1], C. Guiducci[2]
[1]Politecnico di Milano, LaBS, Laboratory of Biological Structure Mechanics, Milano, Italy
[2]Swiss Federal Institute of Technology (EPFL), Laboratory of Life Sciences Electronics - Swiss Up Chair, Lausanne, Switzerland

A model of a cell counter sensor based on Impedance Spectroscopy (IS) has been implemented in COMSOL Multiphysics. The cell counter is a silicon-based microdevice consisting in 3D electrodes placed in a wide microchannel: cells flow in the microchannel through the electrodes to be detected. The model allows to evaluate the functionality of the device depending on geometrical parameters and ...

From CT Scan to Plantar Pressure Map Distribution of a 3D Anatomic Human Foot

S. Gerbino, and P. Franciosa
University of Molise, School of Engineering, Via Duca degli Abruzzi, Termoli, Italy

Understanding the stress-strain behavior of human foot tissues and pressure map distributions at the plantar interface is of interest into biomechanical investigations. In particular, monitoring plantar pressure maps is crucial to establishing the perceived human comfort of shoe insoles. A 3D anatomical detailed FE human foot model was created, starting from CT (Computer Tomography) scans of a ...

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