R. Said, R. Cotton, P. Young, A. Datta , M. Elwassif, and M. Bikson
Simpleware Ltd, Exeter, UK
Department of Biomedical Eng, The City College of New York, USA
Electrical stimulation of the brain involves the application of currents delivered through scalp electrodes to modulate brain activity, known as Transcranial Current Stimulation (TCS). A critical factor for TCS efficacy and safety is the “spatial focality” of induced neuronal modulation. Bikson and coauthors from the City College of New York have been investigating the impact of disc ...
K. Manda, and A. Eriksson
Royal Institute of Technology
100 44 Stockholm, Sweden
Articular cartilage is an avascular connective soft tissue in the diarthrodial joints and functions in a highly demanding mechanical environment. The degeneration or wear of the cartilage is a huge problem that effects millions of people every year. The long term objective of the present work is to develop an analytical articular cartilage growth model. A simplified 2D axisymmetric ...
A. González-Suárez, M. Trujillo, J. Koruth, A. D'Avila, E. Berjano
Biomedical Synergy, Electronic Engineering Department,Universitat Politècnica de Valencia, Valencia, Spain
Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de Valencia, Valencia, Spain
Helmsley Cardiac Electrophysiology Center, Mt SinaiMedicalCenter and School of Medicine, New York, NY, USA
Previous studies proposed using bipolar radiofrequency ablation across two catheters placed on opposing surfaces of the ventricular wall to create transmural lesions. 2D and 3D models were built and solved with COMSOL Multiphysics software. With these models, it was possible to study the temperature distribution and lesion geometry (Figure), to compare the potential of two ways of applying ...
K. Funamoto, I.K. Zervantonakis, R.D. Kamm
Tohoku University, Sendai City, Miyagi, Japan
Massachusetts Institute of Technology
Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.
V. Tidwell, P. LaRosa, M. Zhang, H. Eswaran, A. Nehorai
Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO, USA
Monsanto Company, Technology Pipeline Solutions, St. Louis, MO, USA
OB/GYN Department, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Uterine contractions during pregnancy are currently poorly understood – experts disagree on the mechanisms by which contractions propagate through the organ and the structural layout of the uterine muscle fibers. We have developed a multi-scale model of the uterus, at the cellular, tissue, and organ levels. By comparing simulated abdomen-level magnetic field readings from our model to clinical ...
Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure
P. Ciesielski, M. Crowley, L. Thompson, B. Donohoe, D. Robichaud, A. Sanders, M. Nimlos, T. Foust
Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA
Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions that neglect important characteristics that are unique to biomass particles. These characteristics, including ...
R. Samso, N. Forquet, P. Molle, J. Garcia
Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
IRSTEA, Freshwater Systems, Ecology and Pollution Research Unit, Villeurbanne, France
Horizontal-Flow Constructed Wetlands (HFCWs) are a particular type of biofilter, and as such they rely mostly on the activity of bacterial communities to treat wastewater. Bacterial growth in HFCWs induces dramatic changes in its hydraulic and hydrodynamic behaviour (bioclogging), which may eventually result in overland flow of wastewater. Consequently, clogging is the main cause of premature ...
G. E. Svedberg, L. Lama, J. Gantelius
Science for Life Laboratory, Stockholm, Sweden
Paper based lateral flow assays are widely used as point of care devices for disease diagnostics due to their low cost, short run time and ease of use. Binder molecules specific for certain molecular biomarkers of interest are typically deposited as dots or lines on paper strips, whereupon sample can be flowed through the paper strip via capillary forces in order to measure the concentration of ...
Magnetic Fields and Materials for Medical Bone Reconstruction Assisted by Advanced Finite-Element Simulations
A. Sytcheva and T. Herrmannsdörfer
Hochfeld-Magnetlabor Dresden, Forschungszentrum Dresden-Rossendorf, Dresden, Germany
We address the use of magnetic fields, forces, and materials for medical purposes. In particular, the treatment of osteochondral lesions is aimed for. To support ongoing activities in this field of research, last advances in using Finite Element Analysis (FEA) for the simulation of relevant processes, like magnetic targeting and magnetic fixation are reported. The availability of advanced ...
Image-Based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-Pulmonary Applications
F.K. Hermans, R.M. Heethaar, R.T. Cotton, and A. Harkara
VU University Medical Center, Amsterdam, The Netherlands
Simpleware Ltd., Exeter, United Kingdom
For medical diagnostic purposes there is an increasing need for non- (or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the heart and Electric Impedance Tomography (EIT) is used for investigating lung tissue condition. This paper ...