Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Image Based Mesh Generation for Realistic Simulation of the Transcranial Current Stimulation

R. Said[1], R. Cotton[1], P. Young[1], A. Datta[2] , M. Elwassif[2], and M. Bikson[2]
[1]Simpleware Ltd, Exeter, UK
[2]Department of Biomedical Eng, The City College of New York, USA

Electrical stimulation of the brain involves the application of currents delivered through scalp electrodes to modulate brain activity, known as Transcranial Current Stimulation (TCS). A critical factor for TCS efficacy and safety is the “spatial focality” of induced neuronal modulation. Bikson and coauthors from the City College of New York have been investigating the impact of disc ...

Modeling of Articular Cartilage Growth Using COMSOL

K. Manda, and A. Eriksson
KTH Mechanics
Royal Institute of Technology
100 44 Stockholm, Sweden

Articular cartilage is an avascular connective soft tissue in the diarthrodial joints and functions in a highly demanding mechanical environment. The degeneration or wear of the cartilage is a huge problem that effects millions of people every year. The long term objective of the present work is to develop an analytical articular cartilage growth model. A simplified 2D axisymmetric ...

Computational Modeling to Study the Treatment of Cardiac Arrhythmias using Radiofrequency Ablation

A. González-Suárez[1], M. Trujillo[2], J. Koruth[3], A. D'Avila[3], E. Berjano[1]
[1]Biomedical Synergy, Electronic Engineering Department,Universitat Politècnica de Valencia, Valencia, Spain
[2]Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de Valencia, Valencia, Spain
[3]Helmsley Cardiac Electrophysiology Center, Mt SinaiMedicalCenter and School of Medicine, New York, NY, USA

Previous studies proposed using bipolar radiofrequency ablation across two catheters placed on opposing surfaces of the ventricular wall to create transmural lesions. 2D and 3D models were built and solved with COMSOL Multiphysics software. With these models, it was possible to study the temperature distribution and lesion geometry (Figure), to compare the potential of two ways of applying ...

Design of Microfluidic Device for Cellular Experiment Under Controlled Oxygen Tension

K. Funamoto[1], I.K. Zervantonakis[2], R.D. Kamm[2]
[1]Tohoku University, Sendai City, Miyagi, Japan
[2]Massachusetts Institute of Technology

Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.

Multiscale Electromagnetic Modeling of Contractions in the Pregnant Uterus

V. Tidwell[1], P. LaRosa[2], M. Zhang[1], H. Eswaran[3], A. Nehorai[1]
[1]Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO, USA
[2]Monsanto Company, Technology Pipeline Solutions, St. Louis, MO, USA
[3]OB/GYN Department, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Uterine contractions during pregnancy are currently poorly understood – experts disagree on the mechanisms by which contractions propagate through the organ and the structural layout of the uterine muscle fibers. We have developed a multi-scale model of the uterus, at the cellular, tissue, and organ levels. By comparing simulated abdomen-level magnetic field readings from our model to clinical ...

Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure

P. Ciesielski[1], M. Crowley[1], L. Thompson[1], B. Donohoe[1], D. Robichaud[2], A. Sanders[3], M. Nimlos[2], T. Foust[2]
[1]Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
[2]National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
[3]Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA

Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions that neglect important characteristics that are unique to biomass particles. These characteristics, including ...

Modeling Bioclogging Effects in Constructed Wetlands for Wastewater Treatment

R. Samso[1], N. Forquet[2], P. Molle[2], J. Garcia[1]
[1]Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
[2]IRSTEA, Freshwater Systems, Ecology and Pollution Research Unit, Villeurbanne, France

Horizontal-Flow Constructed Wetlands (HFCWs) are a particular type of biofilter, and as such they rely mostly on the activity of bacterial communities to treat wastewater. Bacterial growth in HFCWs induces dramatic changes in its hydraulic and hydrodynamic behaviour (bioclogging), which may eventually result in overland flow of wastewater. Consequently, clogging is the main cause of premature ...

Simulations of Lateral Flow and Vertical Flow Microarray Assays for Point of Care Diagnostics

G. E. Svedberg[1], L. Lama[1], J. Gantelius[1]
[1]Science for Life Laboratory, Stockholm, Sweden

Paper based lateral flow assays are widely used as point of care devices for disease diagnostics due to their low cost, short run time and ease of use. Binder molecules specific for certain molecular biomarkers of interest are typically deposited as dots or lines on paper strips, whereupon sample can be flowed through the paper strip via capillary forces in order to measure the concentration of ...

Magnetic Fields and Materials for Medical Bone Reconstruction Assisted by Advanced Finite-Element Simulations

A. Sytcheva[1] and T. Herrmannsdörfer[1]
[1]Hochfeld-Magnetlabor Dresden, Forschungszentrum Dresden-Rossendorf, Dresden, Germany

We address the use of magnetic fields, forces, and materials for medical purposes. In particular, the treatment of osteochondral lesions is aimed for. To support ongoing activities in this field of research, last advances in using Finite Element Analysis (FEA) for the simulation of relevant processes, like magnetic targeting and magnetic fixation are reported. The availability of advanced ...

Image-Based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-Pulmonary Applications

F.K. Hermans[1], R.M. Heethaar[1], R.T. Cotton[2], and A. Harkara[2]

[1]VU University Medical Center, Amsterdam, The Netherlands
[2]Simpleware Ltd., Exeter, United Kingdom

For medical diagnostic purposes there is an increasing need for non- (or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the heart and Electric Impedance Tomography (EIT) is used for investigating lung tissue condition. This paper ...

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