Y. Song, and C. Wang
Florida International University, Miami, FL, USA
Enzymatic biofuel cells (EBFCs) are miniature, implantable power sources, which use enzymes as catalysts to perform redox reaction with biological fuels such as glucose. In this study using COMSOL Multiphysics, we use an EBFC chip, having three dimensional, highly dense micro-electrode arrays, fabricated by C-MEMS micro-fabrication techniques. Glucose oxidase (GOx) is immobilized on anodes for ...
L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland
Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, absorption, distribution, metabolism, and excretion properties of a drug. Therefore, the aims of this study are: 1) to ...
BD Medical - Medical Surgical Systems, Helsingborg, Sweden
Anders B Nilsson graduated M. Sc. in engineering physics from Lund University in Sweden. He has been working in the R&D department at BD Medical as principal engineer and project leader since 2005. He uses COMSOL for a wide range of functions, such as early concept development and qualification of products.
T.C. Zhu, B. Liu, X. Liang
University of Pennsylvania, Philadelphia, PA, USA
Singlet oxygen (1O2) is the major cytotoxic agent during photodynamic therapy (PDT). A previously developed model that incorporates the diffusion equation for the light transport in tissue and the macroscopic kinetic equations for the generation of the singlet oxygen, can be used to numerically calculate the distance-dependent reacted 1O2 using finite-element method (FEM). The formula of reacted ...
H. Cai, R.P. Jackson, C. Steele, and S. Puria
Stanford University, Stanford, CA, USA
To support high frequency transmission, the mammalian middle ear construction is unique. The middle ear bones are connected through two mobile joints, the malleus-incus joint (MIJ) and the incudostapedial joint (ISJ). These synovial joints, consisting of joint capsule and synovial fluid inside, play an important role in sound transmission. We developed our current FE model using COMSOL that ...
A. Eed Olamat, U. Hofmann, B. Pohl, and N. Nkemasong
University of Lübeck, Institute for Signal Processing, Lübeck, Germany
In order to investigate the implantation of microprobes into brain tissue, we developed a finite-element and a physical model to replace real biological tissue for mechanical testing. Penetrating forces of a tungsten indenter into a layered structure was investigated with different indentation speeds. Numerical and physical model are in good correspondence to each other and reproduce measured ...
V. Di Virgilio, A. Coll, S. Bermejo, and L. Castañer
Universitat Politecnica de Catalunya, Barcelona, Spain
In this work we want to explore some techniques, microfluidic and electrospray-ionization based, suitable for dynamic microarrays\' fabrication. The fabrication techniques are based on manipulation and self-assembly of selective coated micro and nanobeads. The simulation will include electro-osmotic flow, species transport, and electrostatics.
B. Boulbène, J. Morchain, and P. Schmitz
Université de Toulouse, NSA, UPS, INP, LISBP, Toulouse, France
We present numerical results involving microorganisms adhering to a plane surface submitted to a shear flow. The purpose is to have a better understanding of the removal mechanisms occurring during the cleaning in place of food processing equipments. The biological cell, i.e. the microorganism, is modelled as a rigid obstacle embedded in the bottom wall of the fluid domain. Shear induced ...
An Efficient Finite Element Analysis on an RF Structure Used to Evaluate the Effect of Microwave Radiation on Uveal Melanoma Cells
A. Dulipovici, D. Roman, I. Stiharu, and V. Nerguizian
École de technologie supérieure, Montreal, Quebec, Canada
Concordia University, Montreal, Quebec, Canada
The use of Microwave/RF energy on cancer cells is explored for tumor ablation using medium power level ranging between a few Watts to about 50 Watts. In this research, low power levels, less than 100 mWatt, are used to evaluate the effect of this energy on Uveal melanoma cells by proliferation tests. The COMSOL simulation of the RF structure used to evaluate the radiation energy on ...
O. Richter, F. Suhling, and S. Moenickes
Technische Universität Braunschweig, Germany
The spatial dynamics of the invasion of new species and genetic dispersal is studied under the presumption of rising temperature by using a coherent approach of coupled partial differential equations of the reaction diffusion type. The nonlinear reaction terms model the population dynamics, genetic exchange and competition. Temperature reaction norms of reproduction rates are conferred by a two ...