Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Numerical Homogenization in Multi-scale Models of Musculoskeletal Mineralized Tissues

A. Gerisch[1], S. Tiburtius[1], Q. Grimal[2], and K. Raum[3]
[1]Technische Universität Darmstadt, Darmstadt, Germany
[2]Laboratoire d’Imagerie Paramétrique, UPMC, Paris, France
[3]Julius Wolff Institut & Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany

Musculoskeletal mineralized tissues (MMTs), e.g. bone, are hierarchical composite materials. Their effective elastic properties at different scales are of interest for computational studies of the MMT’s response to mechanical loading but also to realistically simulate implant osseointegration. We combine multi-scale and multi-modal experimental techniques with mathematical modelling of MMTs ...

Investigation of the Effect of Spinal Defects on Spondylolysis and Stress Fracture of Vertebral Bodies

M.S. Yeoman[1], C. Quah[2], A. Cizinauskas[1], K. Cooper[1], D. McNally[5], B. Boszczyk[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]The Centre for Spinal Studies and Surgery, Queen’s Medical Centre, Nottingham, United Kingdom
[5]Bioengineering Research Group, Faculty of Engineering, The University of Nottingham, Nottingham, United Kingdom

Spondylolysis (SL) is a defect of the spinal vertebra, and is typically caused by stress fracture of the pars interarticularis bone of the vertebral arch. It is especially common in adolescents who over train in sporting activities. Spina bifida occulta (SBO) is a malformation of the spine where the protruding vertebral bodies are not fully formed. In this study we demonstrate the predisposition ...

Stochastic Modeling of Biological Systems – Ranking the Model Parameters of the Human Vocal Folds

D. Cook[1]
[1]New York University, New York, USA

Computational models of biological systems are becoming more and more common in medical research areas. Evidence of this can be found by examining the number of articles containing the term “finite element” in the expansive National Institutes of Health (NIH) digital research archive PubMed. Numerical modeling of biological systems allows the execution of “computational ...

Solid Food Pasteurization by means of Ohmic Heating: Influence of Process Parameters

M. Zell[1], D. Cronin[1], D. Morgan[1], F. Marra[2], and J. Lyng[1]
[1]School of Agriculture, Food Science and Veterinary Medicine, Agriculture and Food Science Centre, College of Life Sciences, UCD Dublin, Ireland
[2]Dipartimento di Ingegneria Chimica e Alimentare, Università degli Studi di Salerno, Italy

Pasteurization of solid food undergoing ohmic heating has been analyzed using COMSOL Multiphysics on the basis of a previously validated multiphysics model. The simulation of pasteurization by ohmic heating involves simultaneous solution electrical potential within the food, heat transfer, and the kinetics transport of death of microorganisms. In the model, thermo-physical and electrical ...

A Mean Field Approach to Many-particles Effects in Dielectrophoresis

O. Nicotra, and A. La Magna
CNR-IMM Sezione di Catania, Catania, Italy

One of the major applications for dielectrophoresis is the selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particle effects due to high concentrations of biological material around electrodes can cause a rapid decrease of trapping efficiency in dielectrophoretic devices. In this contribution we present a new approach based on a drift-diffusion dynamics to study ...

Drug Distribution in the Human Eye

L. Murtomäki[1], T. Kainuvaara[1]
[1]University of Helsinki, Helsinki, Finland

Drug therapy of the posterior segment of an eye is very challenging due to the difficult accessibility. Modern drugs often are large molecules, such as peptides, antibodies or oligonucleotides which are administrated, e.g. by intravitreous injections which requires clinical conditions. Computer modeling can be helpful in designing new and less invasive routes of drug administration. COMSOL is ...

Simulation of Radiation Dose Response in Phantom for CT

H. Chen-Mayer[1], R.E. Tosh[1]
[1]National Institute of Standards and Technology, Gaithersburg, MD, USA

The radiation dose produced by an x-ray CT scanner to the patient is conventionally referenced to measurements performed by an ionization chamber in a phantom. On a fundamental level, the radiation absorbed dose, J/kg, can be determined directly by the temperature rise in the absorbing material. We model the temperature response in a high density polyethylene (HDPE) phantom. Use of COMSOL ...

Simulation of Convection in Water Phantom Induced by Periodic Radiation Heating

H.H. Chen-Mayer[1], and R. Tosh[1]
[1]Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA

Water calorimetry is employed to establish a primary reference standard for radiation dosimetry by measuring the temperature rises in a water phantom (a cube of about 30 cm x 30 cm x 30 cm) subjected to a beam of ionizing radiation.  We use COMSOL Multiphysics to model the system using the Heat Transfer module and the Incompressible Navier-Stokes module with a geometry of 2D-axial ...

Validation of Measurement Strategies and Anisotropic Models Used in Electrical Reconstructions

R. Sadleir
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA

We are developing approximations of electrically anisotropic materials for use in novel imaging methods. Our modeling work in COMSOL comprises comparisons of anisotropic and layered models in terms of electrical conductivities measured using different strategies. We tested solution stability in one anisotropic case by varying mesh anisotropy. In our case, good approximations to the true ...

A Biological Gear in the Human Middle Ear

H. Cai, R.P. Jackson, C. Steele, and S. Puria
Stanford University, Stanford, CA, USA

To support high frequency transmission, the mammalian middle ear construction is unique. The middle ear bones are connected through two mobile joints, the malleus-incus joint (MIJ) and the incudostapedial joint (ISJ). These synovial joints, consisting of joint capsule and synovial fluid inside, play an important role in sound transmission. We developed our current FE model using COMSOL that ...

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