Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Growth and Remodelling of Intracranial Saccular Aneurysms

A. Di Carlo[1], V. Sansalone[2], A. Tatone[3], and V. Varano[1]
[1]Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
[2]Laboratoire de Mécanique Physique, Université Paris Est, Paris, France
[3]DISAT, Università degli Studi dell’Aquila, L'Aquila, Italy

We present a mechanical model a growing spherical shell suitable for predicting the evolution of a Saccular Cerebral Artery Aneurysms (SCAA). It relies basically on the Kröner-Lee decomposition, used to describe the interplay between the current and the relaxed configuration of body elements. Rupture or stabilization of a SCAA are the end effect of a number of biological mechanisms, still poorly ...

Solid Food Pasteurization by means of Ohmic Heating: Influence of Process Parameters

M. Zell[1], D. Cronin[1], D. Morgan[1], F. Marra[2], and J. Lyng[1]
[1]School of Agriculture, Food Science and Veterinary Medicine, Agriculture and Food Science Centre, College of Life Sciences, UCD Dublin, Ireland
[2]Dipartimento di Ingegneria Chimica e Alimentare, Università degli Studi di Salerno, Italy

Pasteurization of solid food undergoing ohmic heating has been analyzed using COMSOL Multiphysics on the basis of a previously validated multiphysics model. The simulation of pasteurization by ohmic heating involves simultaneous solution electrical potential within the food, heat transfer, and the kinetics transport of death of microorganisms. In the model, thermo-physical and electrical ...

Study of how electromagnetic characteristics of human abdomen affects B1+ distribution on 3T MR Imaging

A. Nabetani
GE Healthcare Japan Corporation, Japan

It was studied how the permittivity and the conductivity of humans had influence on the transmit B1 magnetic field distribution in the abdominal region. It was also studied how these electromagnetic characteristics affected the static RF shimming which is defined as RF shimming by applying amplitude scaled and phase shifted version of essentially the same RF signal to multiple transmit elements.

Modeling of Swelling in Whey Protein Based Gel Systems

M.H. Oztop, and K.L. McCarthy
University of California, Davis, CA, USA

In this study, Whey Protein Isolate (WPI) gels of different thickness were soaked in solutions of pH 7.0 and mass uptake was recorded. A finite element model based on diffusion and deformed mesh application modes in COMSOL Multiphysics was developed. Deformed mesh application mode provided the opportunity to incorporate the moving boundaries. The moving boundaries were solved by introducing ...

Modeling Antibiotic Diffusion in a Microfluidic Biofilm Array to Study Bacterial Responses to Antibiotic Concentrations and Combinations

J. Deng[1], L. Villegas[1], L. Shor[1], A. Vázquez[2], A. Dhummakupt[3], P. Samson[3], and J.P. Wikswo[3]
[1]University of Connecticut, Storrs, CT, USA
[2]Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico
[3]Vanderbilt University, Nashville, TN, USA

Bacteria within a biofilm typically exhibit higher resistance to antibiotic therapy due to mass transport resistance of the biofilm matrix and/or reduced metabolic activity of cells living within the biofilm interior. The objective of this research was to develop a high-throughput experimental and modeling approach to investigate the effects of colony spacing and concentration on the ...

Fluid Dynamics of Blood Flow During Reperfusion and Post-conditioning

T. Merrill, and A. La Barck
Rowan University, Glassboro, NJ, USA

Reperfusion injury is caused by the rapid restoration of blood flow to oxygen-starved tissue. The model will simulate pulsatile blood flow. A separate 2-dimensional axisymmetric straight tube model will be constructed to simulate the pulsating angioplasty balloon within the flow path. Outlet flow profiles from the straight tube model will then be used as the inlet condition for the ...

Multiphysics Modeling of Applied Stresses and Strains in an Isolated Biologic Cell During Microfluidic Manipulation

Y. Liang[1], A. Saha[1], Z. Shi[1], R. Marcus[1], and S.S. Kohles[2]
[1]Central State University, Wilberforce, OH, USA
[2]Portland State University, Portland, OR, USA

In order to test the hypothesis that a controlled external mechanical stimulus may affect cellular regeneration or degeneration, we developed a three-dimensional computational model to explore the applications of a unique micromechanical environment in COMSOL. Recently, experimental stresses have been applied to living cells suspended by an optical trap within microchannel cross-junctional flows. ...

Predicting the Mechanical Properties of Biological Inspired Diatoms

M.F.D. Moreno, L.P. Davila, and F. Viscarra
University of California at Merced, Merced, CA, USA

Our computational work has focused on calculating the mechanical properties of diatom silica structures using COMSOL Multiphysics. We have used selected diatom geometries based on their structure classification and different loading conditions. Various 3D structures were modeled on Pro/ENGINEER, and then exported to COMSOL for further analysis. The mechanical behavior of diatom structures was ...

Reducing Mitigating Factors That Lead to Clotting of the Arteries From Prolonged Hemodialysis

K. Hegde[1], J. Clark[1], A.G. Akingba[2], and J.V. Clark[1]
[1]Purdue University, West Lafayette, IN, USA,
[2]Indiana University, Indianapolis, IN, USA

In this paper we present a computational study of our novel arteriovenous (AV)-shunt interface device that is expected to reduce the mitigating factors that lead to clotting of the AV-shunts from prolonged hemodialysis. Kidney failure affects about 300,000 (about 0.1%) of the United States population. About 20% of the hemodialysis hospitalizations in the U.S. are due to clotting-related vascular ...

Patient-specific Modelling of Blood-flow in Cerebral Aneurysms

D. Zajarias-Fainsod[1], M.J. Chappell[1], J.F. Collingwood[1], A. Rennie[2], S. Nagaraja[2], and A. Wilson[2]
[1]University of Warwick, Coventry, UK,
[2]University Hospital Coventry and Warwickshire NHS Trust, Coventry, UK

A first stage in this research was to determine the feasibility of patient-specific modelling and the use of in-silico techniques to study flow for the first time in the same vessels with and without an aneurysm. Three-dimensional renderings of the cerebral blood vessels were reconstructed from computed tomography angiograms of the head using MATLAB (The MathWorks) for image processing and ...

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