The performance of a homogeneous T-mixer can be enhanced significantly by the stimulation of secondary/ transverse flows in the microchannel. Various mixing mechanisms are reported for enhancing micromixing performance such as grooves at... COMSOL Conference 2012, Boston M. Jain1 , A. Rao1 , K. Nandakumar1 1 Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, USA
Characterization of particles has numerous applications in science and diagnostics. Recently, particle passage through constrained microchannels has been proposed to characterize particles based on their passage velocity. Nevertheless,... COMSOL Conference 2012, Boston M. Cartas-Ayala1 , R. Karnik1 1 Massachusetts Institute of Technology, Cambridge, MA, USA
Whilst initially developed as a diagnostic aid to improve echogenicity in ultrasound imaging, gas-filled lipid microbubbles are now emerging as a next generation \'theranostic\' tool in the medical arena. Here, their therapeutic potential... COMSOL Conference 2012, Boston M. Conneely1 , V. Hegde2 , H. Rolfsnes1 , A. Mason2 , D. McLean1 , C. Main1 , F.J.D. Smith2 , W.H.I. McLean2 , P.A. Campbell1 1 Carnegie Physics Laboratory, University of Dundee, Dundee, Scotland, United Kingdom 2 Division of Molecular Medicine, University of Dundee, Dundee, Scotland, United Kingdom
Understanding the flow fields at the micro-scale is a key to develop methods of successfully mixing fluids for micro-scale applications. This paper investigates flow characteristics and mixing of three different geometries in... COMSOL Conference 2012, Bangalore V. Ranjan1 , A. Kumar1 , G. Prakash1 , R. Mandal1 1 Department of Mechanical Engineering, Indian School of Mines, Dhanbad, Jharkhand, India
In this paper some discrete parts of a valveless piezoelectric micropump for drug delivery system is designed and simulated. The core components of the micropump are actuator unit that converts the reciprocating movement of a diaphragm... COMSOL Conference 2012, Bangalore L. Nayana1 , P. Manohar1 , S. Babu1 1 Department of Electrical Engineering, Visvesvaraya Technological University, Bangalore, Karnataka, India
Electrokinetic transport of fluids has been investigated both experimentally and numerically due to its various applications in microfluidic devices [1-5]. These devices offer the advantage of transporting fluids or particles to specific... COMSOL Conference 2012, Bangalore P. Parikh1 , A. Sethi1 , S. Benedict1 , D. N. Prasad1 , B. Mallik2 , S. Kapur1 , S. Deb1 , S. Banerjee1 1 BITS Pilani Hyderabad Campus, Hyderabad, Andhra Pradesh, India 2 Megnadh Saha Institute of Technology, Kolkata, India
Cell migration of endothelial cells along gradients is an important process in vivo and an interesting target for cancer therapeutics. Microfluidics offer very powerful tools to study such migration processes in detail in the lab. In this... COMSOL Conference 2012, Milan P. Wallin1 , E. Bernson1 , J. Gold1 1 Chalmers University of Technology, Applied Physics, Biological Physics, Gothenburg, Sweden
Introduction: This work presents the design of a novel flow cell based miniaturized electrochemical respirometer to monitor organic content in water samples semi-continuously, in contrast to current Biochemical Oxygen Demand, BOD,... COMSOL Conference 2012, Milan F.J. del Campo1 , A. Torrents1 , J. Mas2 , F.X. Muñoz1 1 Instituto de Microelectronica de Barcelona, IMB-CNM (CSIC), Campus Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain 2 Departement de Genètica i Microbiologia, Campus Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain
Voids in composite materials can lead to degraded structural performance. The following is a study of voids or bubbles in uncured viscous polymer resin during composites processing. The goal is to determine if voids can successfully... COMSOL Conference 2012, Boston J.J. Gangloff Jr.1 , W.R. Hwang2 , S.G. Advani1 1 Center for Composite Materials, Department of Mechanical Engineering, University of Delaware, Newark, DE, USA 2 School of Mechanical Engineering, Gyeongsang National University, Jinju, Gyeongsangnam-do, Korea
Introduction: Accurate fluid temperature control in microfluidic channels is a requirement for many lab-on-chip and micro-reactors.Thin films resistive metal heaters have proven to be the best choice for localizing heating applications... COMSOL Conference 2012, Milan G. S. Masi1 , S. V. De Guido1 , G. Montagna2 , C. Martucci2 , P. M. Congedo1 , L. Vasanelli 1 , M. G. Manera2 , R. Rella2 1 Department of Innovation Engineering, University of Salento, Lecce, Italy 2 CNR-IMM, Lecce, Italy
With their small size, low manufacturing cost, fast transient response, and capacity to generate fluid power directly from small electrical power sources, microdevices incorporating electroosmostic flow (EOF) have wide-ranging... COMSOL Conference 2012, Boston J. Frey1 , A. Droitcour1 , D. Laser1 1 Wave 80 Biosciences, San Francisco, CA, USA
A microfluidic thermal cycler for Polymerase Chain Reaction (PCR) has been modeled. A microliter sample is driven along the microchannel by a flow generated by means of electroosmotic micropumps, activated in sequence. Several... COMSOL Conference 2012, Milan E. Bianchi1 2 , M.F. Bello1 , I. Critelli1 , G. Dubini1 1 Politecnico di Milano, LaBS, Laboratory of Biological Structure Mechanics, Milano, Italy 2 Swiss Federal Institute of Technology (EPFL), Laboratory of Life Sciences Electronics - Swiss Up Chair, Lausanne, Switzerland
The possibility to detect and probe molecules in microfluidic devices gives rise to interesting applications. There are different approaches how to detect and probe particles, but a common step, for most methods, is to place the particles... COMSOL Conference 2012, Milan D. Kappe1 , A. Hütten1 1 University of Bielefeld, Bielefeld, Germany
The micro-nanometer sized droplets have tremendous applications in bio-diagnostics, polymerization processes etc. In this work, we numerically investigate the droplet formation process of silicone oil in aqueous solution in a MFF device.... COMSOL Conference 2012, Boston Y. Li1 , M. Jain1 , K. Nandakumar1 1 Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, USA
This paper describes the characteristics of MEMS microchannel and various issues of its designing. Here the major parameters are pressure drop and heat transfer rate. Various structures are modeled and optimized to get a minimum pressure... COMSOL Conference 2012, Bangalore S. N. Das1 , G. Bose2 1 Centurion University of Technology and Managment, Jatani, Bhubaneswar, Orissa, India 2 Institute of Technical Education and Research, SOA University, Bhubaneswar, Orissa, India
Piezoelectric buzzers are low cost devices which can be used successfully as actuators in diaphragm-based micro-pumps. The buzzers are piezoelectric wafers (lead-zirconate-titanate-PZT) that are glued on a brass membrane and they are... COMSOL Conference 2012, Boston A. Garcia1 , A. Marcus1 , F. Tejo1 , C. Precker1 , C. Moreira2 1 Universidade Federal de Campina Grande, Campina Grande, PB, Brazil 2 Instituto Federal de Alagoas, Maceio, AL, Brazil
Electric Field Assisted Capillarity (EFAC) is a novel technique for the fabrication of hollow polymer microstructures. It has advantages over current methods as it is a single step process. Hollow microstructures have many uses in... COMSOL Conference 2012, Milan C. Tonry1 , M. K. Patel1 , C. Bailey1 , M. P.Y. Desmuliez2 , W. Yu3 1 Computational Mechanics and Reliability Group (CMRG), School of Computing and Mathematical Sciences, University of Greenwich, London, United Kingdom 2 Microsystems Engineering Centre (MISCEC, School of Engineering & Physical Sciences, Heriot Watt University, Earl Mountbatten Building, Edinburgh, United Kingdom 3 State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, Jilin, China
Electrofluidic transport through a single walled carbon nanotube (SWCNT) is enhanced by electroosmosis. Electroosmosis is made possible in these devices by the combination of a large slip length within SWCNTs and the interfacial potential... COMSOL Conference 2012, Boston G. Zhang1 , 2 , 3 , S.L. Bearden 1 1 Department of Bioengineering, Clemson University, Clemson, SC, USA 2 Department of Electrical and Computer Engineering, Clemson University, Clemson, SC, USA 3 Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
In the emerging field of MEMS microfluidics, micropumps and microvalves are two of the most important devices with a wide spectrum of applications such as programmable drug delivery systems, lab-on-a chip devices, µTAS (micro total... COMSOL Conference 2012, Bangalore D. Samajdar1 , P. Podder1 , A. Bhattacharyya1 , S. Sen1 1 Institute of Radio Physics and Electronics, University of Calcutta, Kolkata, WB, India
The biological hair-cell is a modular building block of a rich variety of biological sensors. These sensors are responsive to various mechanical properties like vibration, touch, gravitational forces, etc., especially flow. Using micro... COMSOL Conference 2012, Bangalore K. Kavitha1 , Y. R. Manjoosha1 , C. S. Sukanya1 , K. Saranya1 , K. Chandra Devi1 , M. Alagappan1 , A. Gupta1 1 Department of Biomedical Engineering, PSG college of technology, Coimbatore, TamilNadu, India
