Brain edema is one of the most common consequences of serious traumatic brain injuries which is usually accompanied with increased Intracranial Pressure (ICP) due to water content increment. A three dimensional finite element model of... COMSOL Conference 2009, Milan X.G. Li1 , H. von Holst1 2 , J. Ho1 , and S. Kleiven1 1 Division of Neuronic Engineering, KTH, Stockholm, Sweden 2 Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
To evaluate the possibility of achieving drug concentration levels required for localized immunosuppression and to optimize sustained, local delivery within small, subcutaneously implanted, prevascularized biohybrid devices designed to... COMSOL Conference 2007, Boston N. Bocca, C. Ricordi, N. S. Kenyon, P. Latta, and P. Buchwald Diabetes Research Institute, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, USA
Study of neurons plays a key role in the fields of basic and medical research aiming at the development of electrically active implants. The Fitzhugh-Nagumo equations are used to model and simulate the spike generation and propagation in... COMSOL Conference 2009, Bangalore R. Appali1 , S. Petersen1 , J. Gimsa2 , and U. Rienen1 1 Institute of General Electrical Engineering, Chair of Electromagnetic Field Theory, University of Rostock, Germany 2 Institute of Biology, Chair of Biophysics, University of Rostock, Germany
We present a preliminary investigation of a Nanoneedle biosensor as an ultra sensitive and localized impedance biosensor using COMSOL.This preliminary study was performed to prove the feasibility of the impedance biosensor for detection... COMSOL Conference 2007, Boston H. Esfandyarpour1,2, A. Maiyegun1, and R. W. Davis2 1Center for Integrated Systems, Department of Electrical Engineering, Stanford University, Stanford, CA, USA 2Stanford Genome Technology Center, Stanford, CA, USA
To support high frequency transmission, the mammalian middle ear construction is unique. The middle ear bones are connected through two mobile joints, the malleus-incus joint (MIJ) and the incudostapedial joint (ISJ). These synovial... COMSOL Conference 2010, Boston H. Cai, R.P. Jackson, C. Steele, and S. Puria Stanford University, Stanford, CA, USA
This paper proposes a FEM model for a segment of a nervous cell axon, which takes into account, through the so called Hodgkin-Huxley equations, the non linear and time varying dynamics of the membrane surrounding it. A combination with... COMSOL Conference 2009, Milan S. Elia1 , P. Lamberti1 , and V. Tucci1 1 Dept. of Electrical and Information Engineering, University of Salerno, Salerno, Italy
Ferrofluids are stable colloidal suspensions of nanosize magnetic particles in an organic or aqueous medium. Suspending nonmagnetic particles within a ferrofluid has led to numerous new areas of study. The simultaneous action of magnetic... COMSOL Conference 2007, Boston A. Kose, B. Fischer, and H. Koser Electrical Engineering Department, Yale University, New Haven, CT, USA
One of the major applications for dielectrophoresis is the selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particle effects due to high concentrations of biological material around electrodes can cause a... COMSOL Conference 2008, Hannover O. Nicotra, and A. La Magna CNR-IMM Sezione di Catania, Catania, Italy
The technique of magnetic drug targeting binds genetic material or drugs to superparamagnetic nanoparticles and accumulates them via an external magnetic field in a target region. However, it is still a challenge for this approach to... COMSOL Conference 2010, Paris A. Heidsieck, and B. Gleich Zentralinstitut für Medizintechnik, TU München, München, Germany
Mechanical tissue properties are required for reliable numerical models of the vocal folds. In this study, criteria for determining the compatibility of tissue property values obtained from independent studies are presented.Two methods... COMSOL Conference 2007, Boston D. D. Cook1, E. Nauman1, and L. Mongeau2 1Department of Mechanical Engineering, Purdue University, West Lafayette, IN, USA 2Department of Mechanical Engineering, McGill University, Montréal, QC, Canada
The use of Microwave/RF energy on cancer cells is explored for tumor ablation using medium power level ranging between a few Watts to about 50 Watts. In this research, low power levels, less than 100 mWatt, are used to evaluate the... COMSOL Conference 2009, Boston A. Dulipovici1 , D. Roman2 , I. Stiharu2 , and V. Nerguizian1 1 École de technologie supérieure, Montreal, Quebec, Canada 2 Concordia University, Montreal, Quebec, Canada
In this paper, we develop an inverse finite-element model for estimating elasticity of the arterial wall. We model the blood flow using COMSOL’s Structural Mechanics module, and use the resulting nonlinear functions corresponding to the... COMSOL Conference 2007, Boston A. Jeremic, and T. Gadkari McMaster Univerisity, Hamilton, ON, Canada
Using Computational Fluid Dynamics, different geometries of side-to-side a-v fistulas for hemodialysis access are evaluated. We created five CAD-models of fistulas with the length of the anastomosis varying from 5 to 15 mm. The five... COMSOL Conference 2007, Grenoble A. K. Niemann1,5, S. A. Kock1, J. V. Nygaard2, E-T. Fründ3, S. E. Petersen4, and J. M. Hasenkam5 1 MR-center, Aarhus University Hospital Skejby, Aarhus, Denmark 2Interdisciplinary Nanoscience Center, Faculty of Science, University of Aarhus, Skejby, Denmark 3Dept. of Radiology, Aarhus University Hospital, "Aalborg Sygehus Syd", Aalborg, Denmark 4Dept. of Urology, Aarhus University Hospital Skejby, Aarhus, Denmark 5Dept. of Cardio-Thoracic and Vascular Surgery, and Clinical Institute, Aarhus University Hospital Skejby, Aarhus, Denmark
Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is... COMSOL Conference 2010, Paris L. Murtomäki, and S. Kotha University of Helsinki, Centre for Drug Research, Helsinki, Finland
Atherosclerosis causes the deposition of plaque on the inner walls of arteries, which leads to restricted blood flow. Using the balloon angioplasty procedure, stents can be inserted and expanded in the atherosclerotic artery. We used... COMSOL Conference 2009, Boston H.C. Wong1 , K.N. Cho1 , and W.C. Tang1 1 Department of Biomedical Engineering, University of California, Irvine, California, USA
A numerical finite element model of one human brain is built in COMSOL in order to study a particular form of hydrocephalus, the so called Normal Pressure Hydrocephalus (NPH). The geometry of the ventricles and the skull is obtained by... COMSOL Conference 2009, Milan K. Shahim1 , J-M. Drezet1 , J-F. Molinari2 , S. Momjian3 , and R. Sinkus4 1 LSMX, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 2 LSMS, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 3 University Hospitals of Geneva and University of Geneva, Switzerland 4 Waves and Acoustics Laboratory, ESPCI, Paris, France
Globally in Otolaryngology industry, Sinusitis is one of the most common diseases related to the nose. Sinusitis is caused when the cilia fail to move the mucus. As a result sinus tissue gets infected that leads to blockage of the... COMSOL Conference 2010, Bangalore T. Selvam, V.P. Kotte, and M. Marimuthu HCL Technologies Ltd, Chennai, Tamil Nadu, India
Three-dimensional FEM method provided by COMSOL is used to model an inhomogeneous advanced breast tumor of different optical properties for outer layer and inner core in a semi-infinite medium. The running time of FEM by COMSOL for one... COMSOL Conference 2010, Boston Y. Xu, and Q. Zhu University of Connecticut, Storrs, CT, USA
Liver metastasis is a major problem in public health. Laser-induced interstitial thermotherapy (LITT) is a recently developed, minimally invasive technique for local tumor destruction within solid organs. This technique consists of... COMSOL Conference 2007, Grenoble B. Wassmer1, R. Viard2, J. Zemmouri1, P. Rochon2, J. Rousseau2, and S. R. Mordon2 1Osyris SA, Hellemmes, France 2INSERM U703 - IFR 114, CHU Lille, Lille, France
In Electrical Impedance Tomography (EIT), an array of surface electrodes is used to inject current and measure the resulting voltages to non-invasively obtain conductivity distributions of objects. The system can be easily implemented as... COMSOL Conference 2007, Boston S. Oh, and R. Sadleir Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
