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Bioengineering Blog Posts

Understanding Drug-Eluting Stents at Boston Scientific

June 18, 2014

Cardiovascular disease is a condition where the arteries in the heart are blocked by plaque. Narrowed arteries can restrict blood flow and cause chest pain and shortness of breath. Bare metal stents can be used to resolve the problem, but excessive tissue can grow over them and narrow the artery again (a process called restenosis). Engineers at Boston Scientific are using simulation to understand the release mechanisms in drug-eluting stents, which can be used to prevent this excess cell growth.

Modeling Bone Strength Using Isotropic and Anisotropic Materials

December 20, 2013

The question of exactly how strong living bones are poses many important considerations for the medical industry. There is not currently a single-purpose device in the field to test bone strength. However, it is possible for researchers to get measurements of bone strength by modeling the entire makeup of the bone and using multiphysics simulation to perform stress and strain analyses. Simulating bone strength starts with a simple map of the external topology of the bone and then delves into […]

Optimizing Dialyzer Design Using Multiphysics Simulation

December 19, 2013

A while back, I had the opportunity to speak with Steven Conrad, a critical care physician at the Louisiana State University (LSU) Health Science Center in New Orleans. Not only is Dr. Conrad a physician as well as a professor at LSU, he’s also a biomedical engineer who uses finite element analysis (FEA) to conduct research on the design of dialyzers. Dr. Conrad uses COMSOL Multiphysics to gain a deeper understanding of the physics behind these devices, and to create […]

Modeling an Accurate Drug Delivery Device

August 22, 2013

There are many different routes through which drugs and other medications can be delivered into a patient’s body during treatment. These include topographical ointments, pills, vaporizers, and injection systems, among others. Many of these drug delivery systems require an enormous amount of precision when it comes to the location, timing, concentration, and amount of the drug to be administered. This is where simulation can be a big help, as it can allow for the modeling of each of these aspects […]

Equation-Based Modeling, a Custom Model of a Beating Heart

May 20, 2013

Equation-based modeling is one of the great strengths of COMSOL Multiphysics. The ability for you to easily access the equations describing the physics you are working with, and adding or manipulating them as you see fit, dramatically opens up the realm of possibilities that you can achieve through modeling and simulation. This is exemplified by the following custom model of a beating heart.

In Silico: Numerical Simulations in Biomedical Engineering

January 30, 2013

Students at Ohio State University can take a course on numerical simulations in biomedical engineering with Richard T. Hart. In the course, they will learn how to use computer modeling to solve biomedical engineering problems. Hart is now providing anyone who is interested in this application area with three video tutorials from the course via the Ohio State University iTunes U page.

Gold Nanorods for Medical Treatment

January 10, 2013

Nanorods are synthetic nanoscale objects used in the area of nanotechnology. They can be synthesized from semiconducting materials or metals, such as gold. The applications of nanorods are many, ranging from display technologies and energy harvesting to cancer therapy.

Improving Ultrasound Imaging Systems by Directing Sound Waves

June 29, 2012

In an earlier blog post, I commented on how acoustic waves are being used in a biomedical setting, to identify malaria in small fluid samples. A more traditional use of piezoelectric devices was written about in the latest COMSOL News. Here, an Italian company, Esaote S.p.A., uses them to produce improved ultrasound imaging systems.

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