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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Control-Release Anesthetics to Enable an Integrated Anesthetic-MSC Therapeutic

T. Maguire [1,2], M. Davis [1], I. Marrero-Berrios [1], C. Zhu [1], C. Gaughan [2], J. Weinberg [3], D. Manchikalapati [3], J. SchianodiCola [3], R. S. Schloss [1], J. Yarmush [3], M. Yarmush [1],
[1] Rutgers University, New Brunswick, NJ, USA
[2] BeauRidge Pharmaceuticals, New York, NY, USA
[3] Department of Anesthesiology, New York Methodist Hospital, Brooklyn, NY, USA

Introduction: While general anesthetics control pain via consciousness regulation, local anesthetics (LAs) act by decreasing sensation in the area of administration by blocking nerve transmission to pain centers. Perioperative intra-articular administration of LAs is a commonly employed ... Read More

Simulation of Bio-medical Waveguide in Mechanical and Optical fields

Y. Xin[1], A. Purniawan[1], L. Pakula[1], G. Pandraud[1], P. J. French[1]
[1]Technology University of Delft, Delft, Netherlands

This paper presents a freestanding waveguide to achieve the goal of detecting anastomosis leakage after colon surgery. The freestanding part is a thin membrane consisting of TiO2 rib and SiN ridge. This freestanding waveguide is designed both mechanically and optically to maintain ... Read More

Effect of Permeability Diminution in Nutrient Diffusion in Intervertebral Disc

M. A. Chetoui [1], O. Boiron [2], A. Dogui [3], V. Deplano [2],
[1] Université de Monastir, Ecole Nationale D'ingénieurs de Monastir; Ecole centrale Marseille, Marseille, France
[2] Aix-Marseille Université, CNRS, Ecole Centrale, Marseille, France
[3] Université de Monastir, Ecole Nationale D'ingénieurs de Monastir, Marseille, France

Intervertebral discs (IVD) are fibro-cartilages situated between vertebrae providing their joint flexibility. They play a major role in the transmission and absorption of load through the spine. The disc can undergo progressive structural and quantitative changes in its composition and ... Read More

Efeito da Pulsação do Ar Durante a Fluidização de Partículas de Amido de Milho

G. C. Dacanal [1], M. G. Thomazi [1], R. Ribeiro [1],
[1] Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos, Pirassununga, SP, Brasil

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Simulation of Microstructured Rolling-Sliding Contacts

M. Weschta[1], S. Tremmel[1], S. Wartzack[1]
[1]Engineering Design, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Bavaria, Germany

To reduce friction in lubricated tribological contacts, the surfaces of the contacting bodies can be microstructured to improve lubricating conditions. For lower loaded contacts this approach has already reached industrial applications, e.g. the piston-liner contact. For higher loaded ... Read More

Design and Simulation of High-Throughput Microfluidic Droplet Dispenser for Lab-on-a-Chip Applications

C. Jin[1], X. Xiong[2], P. Patra[1], R. Zhu[1], J. Hu[3]
[1]Department of Biomedical Engineering, University of Bridgeport, Bridgeport, CT, USA
[2]Department of Electrical and Computer Engineering, University of Bridgeport, Bridgeport, CT, USA
[3]Department of Mechanical Engineering, University of Bridgeport, Bridgeport, CT, USA

Digital Microfluidic Biochip (DMFB) has been widely used in Lab-on-a-Chip (LoC) for disease diagnosis and treatment applications. To quickly convert traditional analog fluidic sample into digital droplets for DMFB processing, a high-throughput microfluidic droplet dispenser device is ... Read More

COMSOL Multiphysics® for Building Energy Simulation (BES) Using BESTEST Criteria

A.W.M. (J.) Van Schijndel [1], D. P. M. Jacobs [1],
[1] Eindhoven University of Technology, Eindhoven, Netherlands

Pioneering Computational Models for the Built Environment Energy performance is becoming more important in the build environment. With better insulated buildings, the possibility of moisture problems and thermal bridges increases. There for, it is not only important to determine the ... Read More

Increasing Heat Transfer in Microchannels with Surface Acoustic Waves

S. Berry[1]
[1]Massachusetts Institute of Technology: Lincoln Laboratory, Lexington, MA, USA

In this numerical study, surface acoustic waves (SAWs) are evaluated as a potential disruptive flow technology for enhancing heat transfer in microchannels. Using COMSOL Multiphysics® software, the physics governing acoustics, single-phase-fluid flow and heat transfer are coupled. The ... Read More

A Concrete Arch Dam under Seismic Loading Conditions

A. Frigerio[1], G. Mazzà[1]
[1]RSE S.p.A., Milan, Italy

A new regulation for the safety assessment of dams has just been developed in Italy and its approval process is still in progress. As a matter of fact the behaviour of dams under seismic loading conditions is deemed of actual interest due to the recent seismic events occurred. In ... Read More

Modeling Self-Potential Effects during Reservoir Stimulation in Enhanced Geothermal System

G. Perillo[1], A. Monetti[2], A. Troiano[2], M. G. Di Giuseppe[2], C. Troise[2], G. De Natale[2]
[1]University of Naples Parthenope, Naples, Italy
[2]INGV-Osservatorio Vesuviano, Naples, Italy

Geothermal systems represent a large resource that can provide, with a reasonable investment, a very high and cost-effective power generating capacity. Despite its unquestionable potential, geothermal exploitation has long been perceived as limited, mainly because of the dependence from ... Read More

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