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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Bioscience and Bioengineering

Computational Modeling to Study the Treatment of Cardiac Arrhythmias using Radiofrequency Ablation

A. González-Suárez[1], M. Trujillo[2], J. Koruth[3], A. D'Avila[3], E. Berjano[1]
[1]Biomedical Synergy, Electronic Engineering Department,Universitat Politècnica de Valencia, Valencia, Spain
[2]Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de Valencia, Valencia, Spain
[3]Helmsley Cardiac Electrophysiology Center, Mt SinaiMedicalCenter and School of Medicine, New York, NY, USA

Previous studies proposed using bipolar radiofrequency ablation across two catheters placed on opposing surfaces of the ventricular wall to create transmural lesions. 2D and 3D models were built and solved with COMSOL Multiphysics software. With these models, it was possible to study the ... Read More

Investigation of the Effect of Spinal Defects on Spondylolysis and Stress Fracture of Vertebral Bodies

M.S. Yeoman[1], C. Quah[2], A. Cizinauskas[1], K. Cooper[1], D. McNally[5], B. Boszczyk[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]The Centre for Spinal Studies and Surgery, Queen’s Medical Centre, Nottingham, United Kingdom
[5]Bioengineering Research Group, Faculty of Engineering, The University of Nottingham, Nottingham, United Kingdom

Spondylolysis (SL) is a defect of the spinal vertebra, and is typically caused by stress fracture of the pars interarticularis bone of the vertebral arch. It is especially common in adolescents who over train in sporting activities. Spina bifida occulta (SBO) is a malformation of the ... Read More

Bone Remodeling Following Total Hip Replacement: Short Stem Versus Long Stem Implants

M.S. Yeoman[1], A. Cizinauskas[1], C. Lowry[2], G. Vincent[3], S. Collins[3], D. Simpson[3]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]Corin Group, Cirencester, United Kingdom
[3]Imoprhics, Manchester, United Kingdom

Bone resorption around hip stems, in particular periprosthetic bone loss, is a common observation post-operatively. A number of factors influence the amount of bone loss over time and the mechanical environment following total hip replacement (THR) is important. Conventional long stem ... Read More

Photon Migration Through Multiple Layers of Biological Tissue

M.S. Yeoman[1], E. Sultan[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]College of Technological Studies, PAAET, Adailiyah, Kuwait

The modeling of light propagation through multiple layers of biological tissue are assessed & compared to the theoretical predictions by Perelman at al. [94 & 95] of the most-favorable-path (MFP). The MFP on which photons will be found can be obtained from the path of the net ... Read More

Electro Thermal Performance Prediction of Radio Frequency Ablation System for Efficient Cancer Treatment

C. Thiagarajan[1], V. Gnanasekar[2]
[1]ATOA Scientific Technologies Pvt Ltd, Whitefield, Bangalore, Karnataka, India.
[2]Perfint Healthcare Pvt. Ltd, T.Nagar, Chennai, India.

Cancer causes significant human deaths. Radiofrequency ablation is an encouraging procedure for cancer treatment. The objective is to demonstrate the multiphysics simulation methodology. This paper summarizes the problem , governing equations, methodology, assumptions, simulation results ... Read More

Nanoporous Silicon Structures for Toxin Detection

H. Ghosh[1], C. R. Chaudhuri[1]
[1]Department of Electronics and Telecommunication, BESUS, Howrah, West Bengal, India

In this project, we are aiming towards the development of an impedimetric biosensor based on nanoporous silicon structures for the detection of small molecular size and low weight food toxins (like Aflatoxin). Existing sensors for such toxin detection fail to achieve high sensitivity ... Read More

A Study on Nutrient Mass Transport through Porous Channeled Flat Sheet Membrane and Prediction of Maximum Scaffold Thickness for Viable Cell Culture (In-vitro) by 3D Modeling for Tissue Engineering Application

N. M. S. Bettahalli[1], B. J. Papenburg [2], D. S. Stamatialis [2], M. Wessling [3]
[1]University of Twente, Enschede, The Netherlands & BMS College of Engineering, Bangalore, India
[2]University of Twente, Enschede, The Netherlands
[3]RWTH Aachen University

Tissue engineering (TE) is a multidisciplinary field involving principles of engineering and life sciences to improve the health and quality of life by repairing, restoring, maintaining, or enhancing tissue and organ function using cells, scaffolds, and growth factors alone or in ... Read More

Studies of Lead Free Piezo-Electric Materials Based Ultrasonic MEMS Model for Bio sensor

P. Pattanaik[1], S. K. Kamilla[1], D. P. Das[2], S. K. Pradhan[3]
[1]MEMS Design Center, Institute of Technical Education & Research (ITER), Sikhya ‘O’ Anushandhan University, Bhubaneswar, Odisha, India
[2]Process Engineering and Instrumentation Lab, Institute of Minerals and Materials Technology (IMMT), Bhubaneswar, Odisha, India
[3]Dept of ECE, Hi-Tech Institute of Technology, Khurda, Odisha, India

This paper describes the design of an ultrasonic transducer using different lead free piezo-electric materials and evaluates their performance with different glucose levels in the human blood. COMSOL Multiphysics 4.2a was used for the simulation study using 2D axis symmetric model of ... Read More

Study of Stent Deformation and Stress Developed at Different Stent Deployment Pressures

K. Basu[1], P. Ghosh[2], A. Chanda[1]
[1]School of Bio Science and Engineering, Jadavpur University, Kolkata, West Bengal, India
[2]Jadavpur University, Kolkata, West Bengal, India

According to clinical reports, cardiovascular disease has become a major global healthcare problem. The deposition of fats, cholesterol etc. at the arterials walls causes thrombus formation leading to stenosis and arterial blockage. To tackle this, along with arterial bypass, the use of ... Read More

Development towards Non-invasive Breast Cancer Imaging using Novel Estrogen Conjugates Fluorescent Dye

Francis .K. J.[1], I. Jose[1]
[1]Christ University,Bangalore, Karnataka,India

Determination of Estrogen Receptor [ER] status is a key in detecting cancer pathogenesis at early stage. In our work we discuss Near Infrared Fluorescence [NIRf] Molecule Optical Imaging Diagnostic modality for early detection of breast cancer. A novel target-specific NIRf dye conjugate ... Read More

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