Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Simulation of the Electrode-Tissue Interface with Biphasic Pulse Train for Epi-retinal Prosthesis

S. Biswas[1], S. Das[2], M. Mahadevappa[2]
[1]Advanced Technology Development Center, Indian Institute of Technology, Kharagpur
[2]School of Medical Science and Technology, Indian Institute of Technology, Kharagpur

Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) are diseases causing blindness in a large number of people. In this type of degenerative disease, mostly the photoreceptors are damaged. Thus attempts have been made to electrically stimulate the surviving inner retinal neurons and retinal ganglion cells (RGC) in order to restore vision. In this paper, the electrode-tissue ...

Design of a Pressure Sensor to Monitor Teeth Grinding

I.M. Abdel-Motaleb[1], K. Ravanasa[1], K.J. Soderholm[2]
[1]Department of Electrical Engineering, Northern Illinois University, DeKalb, IL, USA
[2]Department of Restorative Dental Sciences, College of Dentistry, University of Florida, Gainesville, FL USA

Studying teeth grinding behavior and other oral conditions requires the ability to accurately measure the pressure on the teeth. Placing a sensor in the mouth requires small size devices with powering and measurement techniques that do not hinder the normal life of the patient. To meet these requirements, we designed, using COMSOL, a small, easy to read MEMS capacitive force sensor, with ...

Modeling 3D Calcium Waves from Stochastic Calcium Sparks in a Sarcomere Using COMSOL Multiphysics®

L. T. Izu[1], Z. Coulibaly[2], B. Peercy[2]
[1]University of California-Davis, Davis, CA, USA
[2]University of Maryland, Catonsville, MD, USA

This paper utilizes the COMSOL Multiphysics® general form PDE interface and MATLAB® to model stochastic calcium waves in a sarcomere (basic unit of a heart cell). The model we present here shows the evolution of waves generated from calcium being released stochastically from sites modeled as point sources. The release sites are distributed on z-disc (planes) in a hexagonal pattern, and their ...

Effect of Electrical Field Distortion on Particle-Particle Interaction Under DEP

G. Zhang[1], Y. Zhao[1], J. Hodge[1], J. Brcka[2], J. Faguet[2], E. Lee[2]
[1]Clemson University, Clemson, SC, USA
[2]TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

In using DEP for particle manipulation, researchers often use a formula to calculate the DEP forces in which the forces are proportional to the particle radius to the third power. This formula assumes that the electrical field, E, will not be affected by the presence of a particle, no matter what the actual size and the dielectric property of the particle are. This work confirms that the ...

Modeling Light Propagation in Skin for Visualization of Subcutaneous Veins

H. Kwon[1], R. Huancaya[1]
[1]Andrews University, Berrien Springs, MI, USA

Vein visualization systems such as the VeinViewer are vein-contrast enhancement devices that use an infrared camera to highlight blood or the underlying vasculature and project the image in real time onto the skin. Understanding the light propagation in a realistic skin model is critical, but only a few computational models have been developed to account for this particular system. We have ...

Computational Modeling and Simulation of the Human Duodenum

B. Hari[1], S. Bakalis[1], P. Fryer[1]
[1]The University of Birmingham, School of Chemical Engineering, Edgbaston, Birmingham, United Kingdom

Worldwide attention in the computational modeling and simulation of the human intestine is increasing in order to help understand its complex behavior and improve health. Computational fluid dynamics is an essential tool to understand the mechanics and transport phenomena of the human intestine, thereby advancing the diagnosis and treatment of gastrointestinal related diseases. The aim of this ...

Improving Detection Sensitivity for Nanoscale Targets Through Combined Photonic and Plasmonic Techniques

G. Zhang[1], Y. Zhao[1]
[1]Clemson University, Clemson, SC, USA

Photonic technique such as the whispering gallery mode (WGM) is often used for detection of small particles like bacteria and viruses. It offers good detection sensitivity and is advantageous over other detection techniques because the detection can be label free. However, the detection sensitivity may not be sufficient when the size of the detection target is in nanoscale. To change this, we use ...

Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor

M. A. Kadir[1], S. P. Ahmed[2], G. D. Al Quaderi[3], R. Rahman[2], K. Siddique-e Rabbani[1]
[1]Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
[2]Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
[3]Department of Physics, University of Dhaka, Dhaka, Bangladesh

Focused Impedance Method (FIM), a new technique of electrical impedance measurement having high sensitivity in the central region, can sense the change in transfer impedance of an object embedded at a shallow depth within a volume conductor of unchanging background conductivity, using electrodes at the surface. This paper presents a new method for measuring the volume of such an embedded object ...

Singlet Oxygen Modeling for PDT Incorporating Local Vascular Oxygen Diffusion

T. C. Zhu[1], B. Liu[1]
[1]University of Pennsylvania, Philadelphia, PA, USA

Singlet oxygen (1O2) is the major cytotoxic agent that kills cells during photodynamic therapy (PDT). Based on a previously-developed model, the distance-dependent reacted 1O2 can be numerically calculated using finite-element method. We improved the model to include microscopic kinetic equations of oxygen diffusion from uniformly distributed blood vessels to the adjacent tissue. The blood vessel ...

COMSOL Thermal Model for a Heated Neural Micro-Probe

M. Christian[1], S. Firebaugh[1], A. Smith[1]
[1]United States Naval Academy, Annapolis, MD, USA

This project utilizes the heat transfer module of the COMSOL Multiphysics environment to model the effects that an ohmic heating probe will have on neural tissue. The model quantifies the thermal impact of active components embedded on a neural micro probe by solving the Penne’s bioheat equation with an external MATLAB function to determine the heat generation along the length of the probe. ...

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