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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Bioscience and Bioengineering

Electrohydrodynamic Micropump Modeling for Performance Optimization

A. Mulye[1], S. Potnis[2]
[1]Northeastern University, Boston, MA, USA
[2]VIT, Mumbai, Maharashtra, India

We present an optimized and efficient design of an electrohydrodynamic (EHD) micropump for high performance in microscale and biological applications. We are targeting two major applications, a parylene C design for electrically-actuated medicine delivery, and a silicon-based pump design ... Read More

Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor

M. A. Kadir[1], S. P. Ahmed[2], G. D. Al Quaderi[3], R. Rahman[2], K. Siddique-e Rabbani[1]
[1]Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
[2]Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
[3]Department of Physics, University of Dhaka, Dhaka, Bangladesh

Focused Impedance Method (FIM), a new technique of electrical impedance measurement having high sensitivity in the central region, can sense the change in transfer impedance of an object embedded at a shallow depth within a volume conductor of unchanging background conductivity, using ... Read More

Simulation of the Electrode-Tissue Interface with Biphasic Pulse Train for Epi-retinal Prosthesis

S. Biswas[1], S. Das[2], M. Mahadevappa[2]
[1]Advanced Technology Development Center, Indian Institute of Technology, Kharagpur
[2]School of Medical Science and Technology, Indian Institute of Technology, Kharagpur

Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) are diseases causing blindness in a large number of people. In this type of degenerative disease, mostly the photoreceptors are damaged. Thus attempts have been made to electrically stimulate the surviving inner retinal ... Read More

Electrical Characterization of Biological Cells on Porous Substrate Using COMSOL Multiphysics®

D. Mondal[1], C. RoyChaudhuri[1]
[1]Department of Electronics and Telecommunication Engineering, Bengal Engineering and Science University, Howrah, West Bengal, India

In this paper, the gross electrical characterization of biological cells on porous substrate is analyzed using COMSOL Multiphysics®. Dynamic electrical characterization during cell growth is used as a non-invasive and label-free technique to understand the growth kinetics of cells. It is ... Read More

Computational Analysis on Commercially Available Stent Designs

K. Basu[1], P. Ghosh[2], S. Bhattacharjee[2], S. Das [2], A. Chanda[1]
[1]School of Bio Science and Engineering, Jadavpur University, Kolkata, West Bengal, India
[2]Department of Mechanical Engineering, Jadavpur University, Kolkata, West Bengal, India

Cardiovascular disease has become a major healthcare problem. To tackle this along with bypass surgery, the use of the cardiovascular stent is considered promising and effective. In this study, we aim to find the effectiveness of stent deployments and their influence on haemodynamics ... Read More

Computational design and analysis of Microwave Tomography in Intracerebral Hemorrhage

Priyadarshini Natarajan [1], Rajkumar ElagiriRamalingam[1]
[1]Division of Biomedical Engineering, School of Biosciences and Technology, VIT University, Tamil Nadu, India

Intracerebral hemorrhage is a condition where a blood vessel in the brain ruptures and causes internal bleeding leading to hemorrhagic stroke. 800 in every 100,000 people suffer from stroke each year and it's one of the major causes of mortality worldwide. Diagnosis involves Neurological ... Read More

Multiphysics Modeling and Analysis of DBS Electrodes: Application to Parkinson’s Disease

M.Vidya[1], M. SharatDivya[1], N.Priyadarshini[1], E.R Rajkumar[1]
[1]Division of Biomedical Engineering, Center for Biomedical Engineering Research, School Of Biosciences and Technology, VIT University Vellore, India.

Deep Brain Stimulation (DBS) is a surgical technique that involves surgically implanting Platinum electrode to create an electric field to activate the targeted nerve cells and fibers with minimized side effects. Important stimulation parameters to monitor include temperature, electric ... Read More

Shear Stress Analysis in High-Throughput Dual-micropillar-based Microfluidic Platform

J.Borana[1], J.M.Lee[2], B.G.Chung[2]
[1]Indian Institute of Technology Guwahati, Guwahati, India
[2]Department of Mechanical Engineering, Sogang University, Seoul, Korea

We developed the dual-micropillar-based microfluidic platform to control cellular behavior. The 4×4 dual micro-pillar based platform consists of 16 circular-shaped outer micropillars and 8 saddle shaped inner-micropillars. We simulated various shapes of inner micropillars to analyze the ... Read More

A Practical Method to Model Complex Three-Dimensional Geometries with Non-Uniform Material Properties Using Image-based Design and COMSOL Multiphysics®

J. Cepeda[1], S. Birla[2], J. Subbiah[2], H. Thippareddi[1]
[1]Department of Food Science & Technology, University of Nebraska, Lincoln, NE, USA
[2]Department of Biological Systems Engineering, University of Nebraska, Lincoln, NE, USA

Geometries with heterogeneous material properties are typically defined as a set of multiple parts, each part representing a different material. However, assembling or defining the individual parts of complex geometries can be difficult. A practical method based on image-based mesh ... Read More

Numerical Prediction of Particle Dynamics Within a Cytometer. Application to Counting and Sizing by Impendance Measurement

D. Isèbe[1]
[1]HORIBA Medical, Montpellier, France

This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice–electrode system. The model simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and compute the voltage pulses ... Read More

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