Inertial Focusing, a Counterintuitive Approach to Concentrate Cells

Matheus Fernandes | August 9, 2013

Suppose we have a rectangular microchannel containing a laminar flow with Reynolds number Re = 1. Next, let’s randomly distribute suspended particles at the channel’s inlet. Given that there are no external forces acting on these particles, you would intuitively expect that the particles would trace the fluid streamline. However, scientists from Massachusetts General Hospital (MGH) and Veryst Engineering would disagree, and their research findings suggest a completely different pattern than what would be expected. The researchers claim that depending […]

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Matheus Fernandes | July 31, 2013

When you think of a valve, what is the first thing that comes to mind? Electromagnetic waves, or perhaps, Stokes flow separating charged chemicals in a microchannel system? Maybe neither. The truth is, when researchers try to separate small (in the picoliters region), well-defined sample volumes of chemicals, the dispensing accuracy provided by a mechanical regulator probably won’t suffice. An electrokinetic valve, a type of microfluidic valve, on the other hand, provides the perfect solution by giving researchers the flow […]

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