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Droplet Generation by Means of a Two-Fluid Probe

B.P. Cahill[1], M. Quade[1], G. Gastrock[1], K. Lemke[1], J. Metze[1], and D. Beckmann[1]

[1]Institut für Bioprozess und Analysenmesstechnik e.V., Rosenhof, Heilbad Heiligenstadt, Germany

This paper presents a simulation of the operation of a new type of droplet generation probe. This probe, consisting of two concentrically-arranged tubings, is immersed in a beaker of cell medium so that oil is pumped through the outer tubing at a pumping speed less than fluid is drawn into the inner tubing. In this way, droplets of cell medium are entrained into the outlet tubing forming a segmented flow of homogeneously mixed droplets. The simulation allows the sizing and spacing of the droplets to be ascertained.