Ken Kang-Hsin Wang, and Timothy C. Zhu
Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Singlet oxygen (1O2) is the major cytotoxic agent during type-II photodynamic therapy (PDT). The production of 1O2involves the complex reactions among cancer agent, oxygen molecule, and treatment laser light. The light propagation in tumor tissue is described by the diffusion equation. In this work, an optimization routine is developed to fit the [1O2]rx profile to the simulated necrosis ...
Department of Chemical Engineering, Cairo University, Giza, Egypt
Mixing is a typical unit operation that occurs almost in all chemical industries. Static – alternatively termed motionless – mixers are being widely used due to their low power consumption, low capital investment, minimal maintenance costs and versatility. The traditional helical mixing element is mainly used for in-line blending under laminar and transitional flow conditions. The ...
L. Yuan and P.C. Pedersen
Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA
Finite element models using COMSOL Multiphysics and MATLAB were developed to solve the problem of stress distribution interior homogeneous, isotropic, incompressible elastic solid material under known vertical external compression with a rectangular contact surface. Moreover, comparison between these results and analytical solutions was used to further validate that stress drops off with ...
T. Xu, C.K.A. Mewes, S. Gupta, and W.H. Butler
Department of Physics and Astronomy and Center for Materials for Information Technology, University of Alabama, Tuscaloosa, Alabama, USA
Department of Metallurgical and Materials Engineering and Center for Materials for Information Technology, University of Alabama, Tuscaloosa, Alabama, USA
The Giant Magneto Resistance (GMR) effect is a quantum mechanical effect which can be observed in systems consisting of thin alternating ferromagnetic and non-ferromagnetic layers. Simulation using COMSOL allows the evaluation of the magneto-resistance ratio and the electrical resistances of realistic CPP-GMR devices and opens the possibility to study new device materials and designs.
R. Zúñiga-Quesada, M. Vílchez-Monge, P. Vega-Castillo
Instituto Tecnológico de Costa Rica, Cartago, Costa Rica
This work describes the study of a thermal actuator and modifications to the materials employed in order to decrease power consumption and implementation costs. For this study, we worked on improving the thermal actuator described in the work of T. Ebefors. The criteria for choosing the new materials were lower power consumption, commercial availability, and ease processing. The thermal actuator ...
T. Merrill, A. La Barck, and J. Docimo
Rowan University, Glassboro, New Jersey, USA
FocalCool, LLC, Mullica Hill, New Jersey, USA
Reperfusion injury is caused by the rapid restoration of blood flow to oxygen-starved tissue. Animal studies show that intermittent periods of occlusion (also called post-conditioning) during reperfusion can limit tissue damage to vital organs such as the heart and brain. These studies suggest that the protective effects of post-conditioning relate to the dynamics of blood flow. COMSOL is being ...
New York University, New York, USA
Computational models of biological systems are becoming more and more common in medical research areas. Evidence of this can be found by examining the number of articles containing the term “finite element” in the expansive National Institutes of Health (NIH) digital research archive PubMed. Numerical modeling of biological systems allows the execution of “computational ...
J. Biggs, P. VonLockette, and S. Lofland
Rowan University, Glassboro, New Jersey
Magnetorheological Elastomers (MREs) are a composite that consist of magnetic micrometer sized particles suspended within rubber matrix filler. By placing this material within an external magnetic field during the rubber curing process, the poles of the particles are forced to align and form chains of particles within the matrix. These chains cause the MRE to change its stiffness properties when ...
C.B. Crawford, Y. Shin, and G. Porter
Department of Physics and Astronomy, University of Kentucky, Lexington, Kentucky, USA
Traditionally the design cycle for magnetic fields involves guessing at a reasonable conductor / magnetic material configuration, using FEA software to calculate the resulting field, modifying the configuration, and iterating to produce the desired field. Our method involved solving the classical Laplace equation on regions with imposed boundary conditions, which was implemented ...
A. Jeremic, T. Farncombe, S. Liu, and Y. Abdul-Rehman
Department of Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada
Department of Radiology, McMaster University, Hamilton, Ontario, Canada
Single photon emission computed tomography (SPECT) is a nuclear medicine imaging technique that uses gamma rays. It has been especially useful for bone scans, cardiac perfusion imaging, tumor scans and brain imaging. The main advantage of SPECT imaging is that it can target particular tissue receptors allowing one to focus on the imaging of the diseased tissue. In most cases Monte Carlo ...