Numerical Investigation of a Time-dependent Magnetic Actuation Technique for Tagging Biomolecules with Magnetic Nanoparticles in a Microfluidic System
A. Munir, J. Wang, Z. Zhu, and H.S. Zhou
Worcester Polytechnic Institute, Worcester, MA, USA
The magnetic body forces that act on mono-dispersed magnetic nanoparticles (MNPs) tagged biomolecules in a microfluidic system can be efficiently used in various applications that involve separation and detection including DNA and protein analysis, bio-defense, drug delivery, and pharmaceutical development. In this work, we report an FEM model to demonstrate a novel method of tagging ...
A. Jeremic, and A. Atalla
McMaster University, Hamilton, ON, Canada
In this paper, we develop a mathematical model to simulate the movement of bacteria into and within a capillary segment. Also, we model the transportation through capillary walls by means of anisotropic diffusivity that depends on the pressure difference across the capillary walls. By solving the model using COMSOL, it was possible to predict the concentration of bacteria at points within the ...
R. Godard , J. de Boer, N. Ibrahim, and G. Molina-Cuberos
Royal Military College of Canada, Kingston, ON, Canada
University of Toronto, Toronto, ON, Canada
Campus Espinardo, Murcia, Spain
The Huygens Atmospheric Structure Instrument (HASI) was designed to characterize the physical properties of the lower atmosphere and surface of Titan, the planet-size moon of Saturn. The Relaxation Probe (RP) sensor on the Huygens probe, determined the electrical conductivity in the lower atmosphere of Titan, from 140 km to 40 km. It was suspected that at an altitude above 100km, the booms were ...
T.C. Zhu, and X. Liang
University of Pennsylvania, Philadelphia, PA, USA
Singlet oxygen (1O2) is the major cytotoxic agent in photodynamic therapy (PDT). The reaction between 1O2 and tumor cells defines the treatment efficacy. Based on a previously developed model that incorporates the diffusion equation for the light transport in tissue and the macroscopic kinetic equations for the generation of the singlet oxygen, the distance-dependent reacted 1O2 is numerically ...
Osram Sylvania, Beverly, MA, USA
Thomas Dreeben received his B.A. in Philosophy and Mathematics in 1985, and his Ph.D. in Mechanical Engineering in 1997, both from Cornell University. He has worked in automotive fuel systems at Ford Motor Company, and in turbulence at Sandia National Laboratories. He currently works in lighting research at OSRAM SYLVANIA, where his modeling focuses on fluid mechanics and heat transfer as they ...
H. Lee, and J.V. Clark
Purdue University, West Lafayette, IN, USA
In this paper we present a method to mitigate the effect of thermally-induced noise in Micro-Electro-Mechanical Systems (MEMS) through a force feedback circuit. Inherent noise-induced vibrations, which would be inconsiderable in macro scale, are considered as a limitation in micro- and nano- scale since it diminishes the high performance of MEMS devices. For instance, depending on the stiffness ...
G. Zhu, and Y. Li
Lawrence Technological University, Southfield, MI, USA
Fluids used in biomedical microelectromechanical systems (BioMEMS) devices often exhibit very different flow behavior from those in bulk solutions, which in turn affects the behavior of cells and biomolecules in the device. In this work, we investigate an integrated microfluidic system for living cell culture and assay. The system can be used as a generic platform to study the behavior of ...
Beam Structure As an Acoustic Wave Sensor: A Study of the Effect of Sensor Design on Its Sensitivity to Noise
F. Akasheh, A. Biddle, W.S. Shepard Jr., and B.B.B. Zhang
Tuskegee University, Tuskegee, AL, USA
University of Alabama, Tuscaloosa, AL, USA
The detection and identification of the location of a sound source is commonly done using arrays of microphones. A recent new alternative approach has been proposed which involves the use of continuous structures, such as beams or plates, as acoustic wave sensors. The sound wave impinging on the surface of the structure causes it to vibrate and the measured surface displacements can then be used ...
C. Belavý, G. Hulkó, P. Buček, and S. Lel'o
Slovak University of Technology in Bratislava, Bratislava, Slovakia
Technological processes in the engineering practice from point of view of systems and control theory are frequently in the form of distributed parameter systems (DPS). Techniques of FEM based modeling and design of control synthesis methods of DPS which is acceptable for various technological processes, will be demonstrated on modeling and control of temperature fields of the glass melting ...
J. Maneerote, and P.S. Takhar
International Center for Food Industry Excellence Texas Tech University, Lubbock, TX, USA
Microscale comprised of the scale of food biopolymers at which biochemical reactions and textural changes take place, and the macroscale was the scale of interaction of polymers with surrounding water, vapor and oil phases. Numerous novel equations such as generalized Darcy’s law based fluid transport equations for various phases; near-equilibrium equation governing phase change from liquid ...