See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.


View the COMSOL Conference 2023 Collection

Bioscience and Bioengineeringx

Analysis of Magnetically-coupled Human Body Communications

S. A. Rocke [1], Daniel Ringis [1], Jeevan Persad [1],
[1] Department of Electrical and Computer Engineering, The University of the West Indies, St. Augustine Campus, Trinidad and Tobago

Human body communications (HBC) uses the human body as a transmission medium to connect sensors and actuators in, on or in close proximity to the human body. The HBC approach offers tremendous potential for the design and implementation of emerging personalized healthcare systems, as ... Read More

Skin Variations Impact on Non-Invasive Measurement of Blood Glucose with Interdigital Electrodes

J. Persad [1], S. Rocke [1],
[1] Department of Electrical and Computer Engineering, University of the West Indies, St. Augustine, Trinidad and Tobago

This work aims to investigate the behaviour of a simple interdigital sensor structure for glucose monitoring in response to distortions in the skin-topology and differences in skin undulation during use. The study then extends to consider a flexible sensor structure which is better able ... Read More

Seeding Distribution in the Channel of a Cell Culture Vessel

J. Brcka [1], K. Kagawa [2], S. Ozaki [2], Y. Oshima [3], G. Zhang [4],
[1] Tokyo Electron U.S. Holdings, Inc., Austin, TX, USA
[2] Tokyo Electron, Technology Development Center, Chuo-ku, Kobe, Japan
[3] Tokyo Electron Europe LTD, Stem Cell Technology Centre, Stevenage, United Kingdom
[4] Clemson University, Rhodes Engineering Research Center, Clemson, SC, USA

Conventional cell culture (CC) techniques are advancing significantly with a trend towards a mass production. While plating density (number of cells per volume of culture medium) plays a critical role for some cell types, the initial distribution of these cells is affected by the actual ... Read More

Numerical Analysis on Plasmonic Nano-Cucumber Achieving Large EFs and Wide Tuneability of the Peak

A. Zare [1], E. Cutler [1], H. Cho [1],
[1] Center for Biomedical Engineering & Science, University of North Carolina - Charlotte, Charlotte, NC, USA

INTRODUCTION: Researchers in the biomedical field have recently become interested in the potential applications of plasomics. Surface plasmon resonance based on optical properties of metallic nanostructures can be used for detection of special biological targets. Gold nanostructures with ... Read More

Fluid Dynamic Analysis of the Multi-Lumen Thoracic Catheter

S. Budar [1], A. Ritter [1]
[1] Department of Chemistry, Chemical Biology & Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA

In order to achieve an optimized design of the Multi-Lumen Thoracic Catheter (MLTC), fluid dynamics analyses were conducted utilizing COMSOL Multiphysics® software with LiveLink™ for Solidworks®. Lumen placement, diameters, and termination points were adjusted to ensure maximum drainage ... Read More

Design of a Dielectrophoretic Based Micropipette for Gene Expression Applications Using COMSOL Multiphysics® Software

D. Wijesinghe [1], K. Nawarathna [1],
[1] Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND, USA

We have used COMSOL Multiphysics® software to design a micropipette for single -cell gene expression profiling. The micropipette design allows us to insert it into a single-cell to extract genes through dielectrophoresis. As dielectriphoretic force depends on the applied electric field ... Read More

Thermal-Optical Modeling of a Signal Enhancement Approach for Paper-Based Diagnostics

D. Gasperino [1]
[1] Intellectual Ventures Laboratory, Bellevue, WA, USA

INTRODUCTION: Point of care diagnostics aimed at low-resource settings need to be relatively simple, robust and low-cost. The most commonly-used diagnostic platform in these settings is the lateral flow assay (LFA). LFAs are paper-based immunoassays designed to perform on-strip binding ... Read More

A Numerical Model of Electroporation in Bacteria

J. L. Moran [1], N. N. Dingari [1], C. R. Buie [1],
[1] Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

Electroporation is a biotechnological technique which subjects cells to strong (~kV/cm), short (~ms) electric field pulses that open pores on the cells’ plasma membranes. Under the appropriate conditions, the pores mediate the passage of exogenous material into cells. If the pores ... Read More

Modeling a Lung-on-a-Chip Microdevice

M. J. Hancock [1], N. Elabbasi [1],
[1] Veryst Engineering, LLC., Needham, MA, USA

Organ-on-a-chip microdevices combine microfluidics, MEMS, and biotechnology techniques to mimic the multicellular architectures, tissue-tissue interfaces, physicochemical microenvironments, and vascular perfusion of the body.[1] Such devices are being developed to provide better levels ... Read More

Simulating Corrosion in a Crevice of Commercial Pure Titanium

G. Zhang [1, 2, 3],
[1] Department of Bioengineering, Clemson University, Clemson, SC, USA
[2] Department of Electrical and Computer Engineering, Clemson, SC, USA
[3] Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA

Implant devices are assistive devices surgically placed in the human body to restore the functionality of organs and tissues. Metallic implants are often used for load bearing applications including the hip and knee joints. To allow maximum flexibility during surgery for surgeons to pick ... Read More