See How Multiphysics Simulation Is Used in Research and Development


Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Can Oscillatory Convection Accelerate Signal Propagation in Simple Epithelium?

M. Nebyla[1], M. Pribyl[1]
[1]Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic

We introduce a mathematical model of signal transmission in simple epithelial layers. The mathematical model consists of reaction-transport equations for extracellular ligands, cellular receptors, ligand-receptor complexes and a ligand releasing protease. We consider diffusion and ... Read More

Development of an Oxygen-Conserving Mask for Pediatric Patients in Low-Resource Settings

D. Gasperino [1]
[1] Intellectual Ventures Laboratory, Bellevue, WA, USA

Worldwide, the leading cause of mortality in children is acute respiratory infection, primarily associated with pneumonia. One of the essential tools used to treat life-threatening hypoxemia due to pneumonia is the appropriate use of supplemental oxygen. While oxygen therapy is ... Read More

A Numerical Heat Transfer Analysis on an Implantable Phase-Change Actuated Peristaltic Micropump

F. Forouzandeh [1], D. A. Borkholder [1],
[1] Rochester Institute of Technology, Rochester, NY, USA

Advances in protective and restorative biotherapies have created new opportunities to address vestibular disorders, deafness, and noise induced-, sensorineural-, and age-related hearing loss. Controllable and implantable drug delivery micropumps are essential for therapy development in ... Read More

植入电极阵列的人体耳蜗模型仿真 new

李福祥 [1]
[1] 清华大学

对于神经性听力缺陷患者而言,人工耳蜗是目前主要的恢复手段。人工耳蜗通过植入体内的电极阵列产生电流,直接刺激耳蜗的螺旋神经节细胞,引起听觉系统响应。因此,研究植入耳蜗内电极阵列产生的电势分布特点具有重要意义。基于电势分布情况,可以对电极阵列的结构、尺寸、激励方式等进行优化,以提高人工耳蜗的性能。研究中使用的耳蜗以及电极阵列仿真模型为经过其他三维建模软件得到的STL文件导入COMSOL中生成。为了研究耳蜗内电势分布,选择了“电流(ec)”物理场接口,对模型边界设置了电势条件,对部分电极设置了激励电流条件。仿真模型的材料使用了库材料和自定义材料 ... Read More

FEM Analysis and Optimization of Electro-Stimulating Implants for Bone Regeneration and Prevention of Bacterial Infection

T. Bender [1], J. Ziebart [2], T. J. Dauben [1], B. Kreikemeyer [3], R. Bader [2]
[1] Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany; Research Laboratory for Biomechanics and Implant Technology, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany
[2] Research Laboratory for Biomechanics and Implant Technology, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany
[3] Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany

The aim of this study is to investigate the influence of electro-magnetic stimulation on bone regeneration and the effect on bacterial infection. Electro-magnetic stimulation is a promising technique and a powerful tool for the enhancement of bone regeneration. To optimize the amplitude ... Read More

Evaluation of Performance of Enzymatic Biofuel Cells with Microelectrode Arrays Inside a Blood Artery via Finite Element Approach

C. Wang[1], Y. Song[1]
[1]Florida International University, Miami, FL, USA

Enzymatic biofuel cells (EBFCs) are considered as a promising candidate for powering miniature implantable devices. In order to predict the performance in the human blood artery, we simulated a 3D EBFC chip with highly dense micro-electrode arrays. In this simulation using COMSOL ... Read More

Keynote Talk: Building a Better Pump for Heart Failure Patients

[1] F. Hansen
Abbott Laboratories, Pleasanton, CA, USA [1]

Abbott’s Mechanical Circulatory Support group build implants that help people suffering from heart failure, a deadly and increasingly common disease. We combine computational fluid dynamics and particle tracing simulations to optimize the designs of implantable blood pumps that replace ... Read More

Temperature Excursions at the Pulp-Dentin Junction during the Curing of Light-Activated Dental Restorations

M. Jakubinek[1,2], C. Neill[1], C. Felix[3], R. Price[2,3], M. White[1,2]

[1]Departments of Chemistry and Physics, Dalhousie University, Halifax, NS, Canada
[2]Institute for Research in Materials, Dalhousie University, Halifax, NS, Canada
[3]Department of Dental Clinical Sciences, Dalhousie University, Halifax, NS, Canada

Heat produced during the curing of light-activated dental restorations could damage the dental pulp. Given the prevalence of composite restorations and the importance of avoiding injury to the pulp, efforts should be made to minimize the temperature increase that occurs at the pulp ... Read More

Wireless Power and Communications for Implantable Biosensors

C. Romero[1], M. Mujeeb-U-Rahman[1]
[1]California Institute of Technology, Pasadena, CA, USA

Implantable biosensors have the potential to revolutionize the healthcare industry by allowing patients and their health care providers to continuously monitor blood pH levels, pCO2, proteins, metabolites, and a wide variety of other biomolecules. These devices need to operate completely ... Read More

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