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Explore the innovative ways multiphysics simulation is being used worldwide to advance research

Multiphysics modeling and simulation drives innovation across industries and academia — as is evidenced by the many uses showcased in the technical papers and posters presented by engineers, researchers, and scientists at the COMSOL Conference each year.

Draw inspiration from the recent proceedings collected below, or, to find a specific presentation or filter by application area or conference year/location, use the Quick Search tool.

View the COMSOL Conference 2026 Collection

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Interaction of Microparticles in a Miniaturized Vacuum-Cleaner

I. S. M. Jimidar [1], Y. Vanderheyden [1], H. Gardeniers [2], G. Desmet [1],
[1] Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
[2] Universiteit Twente, Mesoscale Chemical Systems MESA+, Enschede, The Netherlands

The ever-growing complexity of samples which need to be processed in e.g., environmental and biomedical/biochemical research, demand higher efficiencies of analytical techniques. Liquid chromatography (LC), mass spectrometry, among others, are analytical techniques that revolutionized ... Read More

Simulation of CMOS Compatible Sensor Structures for Dielectrophoretic Biomolecule Immobilization

H. Matbaechi Ettehad [1], S. Guha [1], C. Wenger [1],
[1] IHP, Frankfurt (Oder), Brandenburg, Germany

The aim of this paper is to optimize with COMSOL Multiphysics® simulation, the design geometry of a near field biosensor which could be used for dielectrophoretic (DEP) immobilization and simultaneous sensing of biomolecules of the order of nanometers to micrometers. COMSOL Multiphysics® ... Read More

Non-linear DC Electrophoresis in High Electric Field Conditions

E. Ruiz-Reina [1], F. Carrique [1],
[1] University of Málaga, Málaga, Spain

Very recently, the synthesis and experimental study of a new class of highly charged polymer particles has been described, which spontaneously charge in non-aqueous low-polarity solvents [1,2]. These suspensions are an example of what is known as salt-free systems. The study of ... Read More

On the Modeling and Simulation of Electroosmotic Micropump for Biomedical Applications

M. Badran [1],
[1] Future University in Egypt, Cairo, Egypt

Non-mechanical micropumps, which does not required moving parts, have prominent role in several biomedical microsystems such as drug delivery, and lab on a chip. Electroosmotic micropump is a non-mechanical micropump that is used to move electrically neutral fluids through very small ... Read More

Nanofluidic Analyte Preconcentration Using Fluid Field-Effect Diodes

A. Eden [1], K. Scida [1], J. C. T. Eijkel [2], C. D. Meinhart [1], S. Pennathur [1],
[1] University of California, Santa Barbara, CA, USA
[2] University of Twente, Enschede, Netherlands

Introduction Throughout the field of micro- and nanoscale electrokinetics, floating bipolar electrodes (BPEs) have proven to be useful in manipulating charged ionic species and biomolecules for electroanalytical studies. The growing use of integrated electronics in working towards fully ... Read More

Study of Rotation of Ellipsoidal Particles in Combined Simple Shear Flow and Magnetic Fields

C. Wang [1], J. Zhang [1],
[1] Department of Mechanical and Aerospace Engineering, Missouri University of Science and Technology, Rolla, MO, USA

This study creates a 2D fluid-structure interaction (FSI) model to study the effect of magnetic field and particle aspect ratio on the period of rotation and symmetry of ellipsoidal paramagnetic particles. The results show that the magnetic field strength has a significant effect on the ... Read More

Dynamic Simulation of a Polymer Molecule Using COMSOL Multiphysics®: DNA Separation in a Microchannel

J. Park [1], S. Monjezi [1], M. Palaniappan [1], J. D. Jones [1], B. Behdani [1],
[1] Missouri University of Science and Technology, Rolla, MO, USA

In this study, COMSOL Multiphysics was used to simulate DNA separation within a microchannel based on the entropic trapping mechanism. The entropic trapping mechanism involves DNA molecules passing through a series of obstacles in a microchannel and different lengths of DNA exhibiting ... Read More

Microfluidic Simulation of a Separation System of T.cruzi from Blood Samples

S. L. Florez [1], M. J. Noguera [1], A. L. Campaña [1], J. C. Cruz [1], J. F. Osma [2],
[1] Department of Biomedical Engineering, University of Los Andes, Bogotá, Colombia
[2] Department of Electrical and Electronics Engineering, Microelectronics Center, University of Los Andes, Bogotá, Colombia

In 2014, it was estimated that there are between 6 to 7 million people worldwide infected by Chagas disease and approximately 25 million people are currently at risk. The parasite Trypanosoma cruzi (T. cruzi) causes this disease and according to the World Health Organization (WHO) it can ... Read More

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