R. Sikorski, B. Chapman, T. Merrill
Rowan University, Glassboro, NJ, USA
A CFD cardiac catheter model was developed to determine the potential for blood hemolysis during administration of local therapeutic hypothermia using a CoolGuide catheter. In vivo animal studies have shown that mild hypothermia may reduce reperfusion injury often associated with heart attack. The CoolGuide Catheter System (CCS) delivers rapid local cooling through a cardiac catheter, reducing ...
J. Xi, Q. M. Mohamad, Y. E. Yuan, J. Rohlinger
Mechanical and Biomedical Engineering, Central Michigan University, Mount Pleasant, MI, USA
1. Flow-induced uvula deformation considerably altered the flow dynamics inside the nose. 2. For a weak soft palate, complete flow occlusion can occur (sleep apnea). 3. Vibration of the airway structures is crucial to better understand snoring generation mechanisms and breathing-related disorders.
Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties - new
K. Cluff, H. Mehraein, G. Jayakumar
Bioengineering, Wichita State University, Wichita, KS, USA
Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA
An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical imaging and computational fluid dynamics (CFD) in a time dependent study allowed the determination of wall ...
S. Hossain , F. A. Mohammadi 
 Department of Electrical and Computer Engineering, Ryerson University, Toronto, ON, Canada
INTRODUCTION: Abnormalities in local body surface temperature have been recognized as a sign of disease for centuries, much before humans knew about the cause of ailments or of pain . The idea of this work is to use numerical simulation tools to predict the location, size and metabolism of tumor embedded in any outer body organ of human. Idealized thermal data of an organ, modeled either as a ...
B. Boulbène, J. Morchain, and P. Schmitz
Université de Toulouse, NSA, UPS, INP, LISBP, Toulouse, France
We present numerical results involving microorganisms adhering to a plane surface submitted to a shear flow. The purpose is to have a better understanding of the removal mechanisms occurring during the cleaning in place of food processing equipments. The biological cell, i.e. the microorganism, is modelled as a rigid obstacle embedded in the bottom wall of the fluid domain. Shear induced ...
V. Nicolas[1,2], J.P. Ploteau, P. Salagnac, P. Glouannec, V. Jury, and L. Boillereaux
Laboratoire d’Ingénierie des MATériaux de Bretagne – Equipe Thermique et Energétique, Université Européenne de Bretagne, Lorient Cedex, France
Laboratoire d’Etudes des Phénomènes de Transfert et de l’Instantanéité : Agro-industrie et Bâtiment, Université de La Rochelle, La Rochelle Cedex, France
Laboratoire de Génie des Procédés, Environnement, Agroalimentaire, ENITIAA, France
In this paper, we present a first model carried out with COMSOL Multiphysics to model bread baking, considering heat and mass transfer coupled with the phenomenon of swelling. This model predicts the pressures, temperatures and water contents evolutions in the dough for different energy requests. First results obtained are analyzed according to various physical parameters in order to better ...
Optimizing Performance of Equipment for Thermostimulation of Muscle Tissue using COMSOL Multiphysics
J. Kocbach, K. Folgerø, L. Mohn, O. Brix
Christian Michelsen Research, Bergen, Norway
Luzmon Norway, Bergen, Norway
Michelsen Medical, Bergen, Norway
The design challenge for thermostimulation equipment is to get a combination of high electric field strength and high temperature within the muscle tissue without causing pain or skin burns. In the present work, COMSOL Multiphysics is used to simulate the temperature distribution and electric field distribution within body tissue for varying body composition and varying design parameters of the ...
J. Ferdous, M. Ghaly , V. B. Kolachalama , T. Shazly[1,4]
Biomedical Engineering Program, University of South Carolina, Columbia, SC, USA
Department of Biomedical Engineering, North Carolina State University, Raleigh, NC, USA
Charles Stark Draper Laboratory, Cambridge, MA, USA
Department of Mechanical Engineering, University of South Carolina, Columbia, SC, USA
Inferior vena cava (IVC) filters have become essential components in deep vein thrombosis treatment to prevent preventing pulmonary embolisms. Filter efficacy relies on maintaining IVC patency by preventing filter-induced thrombosis following clot capture. A computational model has been developed to determine whether a candidate filter design elicits hemodynamic patterns that promote thrombus ...
D. Iber, D. Menshykau, and P. Germann
Department of Biosystems Science and Engineering
Organogenesis is a tightly regulated process that has been studied experimentally for decades. Computational models can help to integrate available knowledge and to better understand the underlying regulatory logic. We are currently studying mechanistic models for the development of limbs, lungs, kidneys, and bone. We have tested a number of alternative methods to solve our spatio-temporal ...
An Elastic and Hyperelastic Material Model of Joint Cartilage - Calculation of the Pressure Dependent Material Stress in Joint Cartilage
T. Reuter, and M. Hoffmann
Research Centre of Medical Technology and Biotechnology
Bad Langensalza, Germany
In this paper we introduce a elastic and hyperelastic model to describe the pressure dependent material stress in joint cartilage. We used the pressure dependent E-modulus E = f(s) to calculate the material stress. E = f(s) is a degree 4 polynomial . The indentor was pressed 0.4 mm into the tissue. The results show that the maximal stress at the contact zone between indentor and cartilage ...