K. Gladine , J. Soons , J. Dirckx 
 University of Antwerp, Belgium
The ear doesn’t solely listen but it also speaks. Sounds formed in the inner ear which are measurable in the outer ear are called Otoacoustic emissions (OAEs). Some claim these are produced by the outer hair cells (OHCs), the amplifiers in the inner ear. Our hypothesis is that the OHCs only amplify distortion products (DPs) but do not produce them.
A. Altamirano, C. Toledo, A. Vera, R. Muñoz, and L. Leija
Centro de Investigacion y Estudios Avanzados
Instituto Politecnico Nacional
In this article, the aim is to study different types and forms of electromyography (EMG) electrodes, for bipolar configuration, and the electric interface with muscle phantom. COMSOL Multiphysics allows modeling shapes and contact surfaces. Surface and needle electrodes will be modeled. A number of different trials and combinations will be presented; exploring different geometric shapes and ...
A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry
Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernström, Ralf Morgenstern, and Michael Hanke
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. bioactivation ...
Estudo Numérico da Eletroquimioterapia em Tumor Cutâneo com Diferentes Configurações de Eletrodos - new
G. Neves, D. Suzuki, J. Alvim, M. Rangel
Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil
Vet Câncer Oncologia Veterinária, São Paulo, SP, Brasil
A eletroquimioterapia é um tratamento de câncer que utiliza a combinação de agentes quimioterápicos e campos elétricos. A base teórica por trás dessa aplicação é a eletroporação. Esse fenômeno biológico consiste na abertura de poros na membrana celular devido à aplicação de pulsos elétricos. Este trabalho analisa o comportamento do campo elétrico gerado por pulsos elétricos aplicados em ...
J. Bergstrom , N. Elabbasi ,
 Veryst Engineering, Needham, MA, USA
The use of thermoplastic materials is increasing and it is becoming more important during the design process to accurately represent the non-linear material response in relevant loading conditions. The COMSOL Multiphysics® software supports advanced modeling capabilities for large deformation analyses, including contact and multiphysics couplings. It is now also possible to use advanced non ...
COMSOL Multiphysics® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology
F. Rossi and R. Pini
Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy
In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation mode and diffusion approximation were used to design a theoretical model of blue LED light interaction with an ...
B. Boulbène, J. Morchain, and P. Schmitz
Université de Toulouse, NSA, UPS, INP, LISBP, Toulouse, France
We present numerical results involving microorganisms adhering to a plane surface submitted to a shear flow. The purpose is to have a better understanding of the removal mechanisms occurring during the cleaning in place of food processing equipments. The biological cell, i.e. the microorganism, is modelled as a rigid obstacle embedded in the bottom wall of the fluid domain. Shear induced ...
S. Curet, M. Mazen Hamoud-Agha
GEPEA, UMR 6144, CNRS, ONIRIS, Université de Nantes, Nantes, France
In this study, COMSOL®4.2a is used to model a microwave heating process in a TE10 rectangular waveguide. The sample consists of a small cylindrical Ca-alginate gel (D = 8 mm, H = 10 mm) inoculated with bacteria Escherichia Coli K12. The sample is placed along the microwave propagation direction into the waveguide. Maxwell’s equations and heat transfer are coupled to a microbial inactivation ...
The Effects of the Electrical Double Layer on Giant Ionic Currents through Single Walled Carbon Nanotubes
G. Zhang[,][,], S.L. Bearden 
Department of Bioengineering, Clemson University, Clemson, SC, USA
Department of Electrical and Computer Engineering, Clemson University, Clemson, SC, USA
Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
Electrofluidic transport through a single walled carbon nanotube (SWCNT) is enhanced by electroosmosis. Electroosmosis is made possible in these devices by the combination of a large slip length within SWCNTs and the interfacial potential at the solution/nanotube interface. A computational model of a SWCNT device was developed using COMSOL Multiphysics to investigate the complete electrical ...
M. Huet ,
 Department of Biotechnology, CEA/Université Grenoble-Alpes, Grenoble, France
A microfluidic component was designed to collect blood from a finger prick by capillary flow and to perform biological analysis. It was used to perform ABO blood typing experiments in one step, the blood drop deposit, by agglutination of red blood cells (RBC) using embedded dried reagents. The present study is a first step in the modeling of the whole agglutination assay. Blood typing ...