Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Cellular Scale Model of Stratum Corneum

R. Santoprete[1], B. Querleux[1]
[1]L'Oréal, Paris, France

To better quantify the impact of the morphological and mechanical properties of the main constituents of the stratum corneum (SC, the outermost layer of the skin) on its overall mechanical behavior, we developed a biomechanical model of the SC at a cellular scale, based on in vitro morphological and mechanical data. The sensitivity analysis quantified the relative impact of the mechanical and ...

Multiphysics Modelling and Simulation of Implantable Wireless MEMS Capacitive Sensor for Cardiovascular Diagnostics

R.Yogeswari[1], S.Venkateshwaran [1], K.Umapathi[1]
[1]United Institute of Technology,Coimbatore,Tamil Nadu, India

Monitoring the Central aorta is a more effective way to diagnose cardiovascular diseases than conventional techniques. Approximately, six million people in the world are currently living with aortic aneurysm and every year 750,000 new cases are diagnosed. This paper presents the design and simulation of biocompatible Wireless MEMS sensor for detection of intraoperative leaks of the stent graph ...

Virtual Modeling of Thermo-Physiological Comfort in Clothing

P. Van Ransbeeck [1], R. Benoot [1], B. Van Der Smissen [1]
[1] University College Ghent, Faculty of Science and Nature, Department of Mechatronics, Belgium

This publication aims to investigate conjugate heat and mass transfer around a clothed virtual manikin. This research can be performed at different scales: (1) at material scale where a piece of textile is investigated in 1D or 2D space or (2) at system level where a clothed cylindrical body (2D) or a complete manikin (3D) is modeled. The work is based on previous methods and results from ...

Can Oscillatory Convection Accelerate Signal Propagation in Simple Epithelium?

M. Nebyla[1], M. Pribyl[1]
[1]Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic

We introduce a mathematical model of signal transmission in simple epithelial layers. The mathematical model consists of reaction-transport equations for extracellular ligands, cellular receptors, ligand-receptor complexes and a ligand releasing protease. We consider diffusion and nonstationary convective transport of protein ligands in the extracellular space. The study was carried out using ...

Estudo Numérico da Eletroquimioterapia em Tumor Cutâneo com Diferentes Configurações de Eletrodos - new

G. Neves[1], D. Suzuki[1], J. Alvim[1], M. Rangel[2]
[1]Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil
[2]Vet Câncer Oncologia Veterinária, São Paulo, SP, Brasil

A eletroquimioterapia é um tratamento de câncer que utiliza a combinação de agentes quimioterápicos e campos elétricos. A base teórica por trás dessa aplicação é a eletroporação. Esse fenômeno biológico consiste na abertura de poros na membrana celular devido à aplicação de pulsos elétricos. Este trabalho analisa o comportamento do campo elétrico gerado por pulsos elétricos aplicados em ...

Magnetic Fields and Materials for Medical Bone Reconstruction Assisted by Advanced Finite-Element Simulations

A. Sytcheva[1] and T. Herrmannsdörfer[1]
[1]Hochfeld-Magnetlabor Dresden, Forschungszentrum Dresden-Rossendorf, Dresden, Germany

We address the use of magnetic fields, forces, and materials for medical purposes. In particular, the treatment of osteochondral lesions is aimed for. To support ongoing activities in this field of research, last advances in using Finite Element Analysis (FEA) for the simulation of relevant processes, like magnetic targeting and magnetic fixation are reported. The availability of advanced ...

Drug Distribution in the Human Eye

L. Murtomäki[1], T. Kainuvaara[1]
[1]University of Helsinki, Helsinki, Finland

Drug therapy of the posterior segment of an eye is very challenging due to the difficult accessibility. Modern drugs often are large molecules, such as peptides, antibodies or oligonucleotides which are administrated, e.g. by intravitreous injections which requires clinical conditions. Computer modeling can be helpful in designing new and less invasive routes of drug administration. COMSOL is ...

Modeling Plant Morphodynamics in Predefined COMSOL Multiphysics® Interface

S. Nikolaev[1], A. Trubuil[2]
[1]Institute of cytology and genetics SB RAS, Novosibirsk, Russia
[2]Institut National de la Recherche Agronomique, Jouy-en-Josas, France

We used a predefined COMSOL Multiphysics® interface to imitate biological growth and shape change (morphodynamics). We found a set of parameters that supply observed morphodynamics for an Arabidopsis embryo during its transition from globular to heart stage.

FEM Simulation of Magnetically Triggered Hydrogel Micro Particles as Advanced Drug Carriers - new

O. Yassine[1], M. Kavaldzhiev[1], J. Kosel[1], Q. Li[1], A. Alfadhel[1], A. Zaher[1]
[1]Electrical Engineering Division, CEMSE Group, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia

Thermally responsive microgel Poly (N-isopropylacrylamide), particles are embedded with iron oxide nanobeads creating magneto-thermally responsive microparticles (MTMs). The magnetic losses in the nanobeads activate the PNIPAM by heating it up to its lower critical solution temperature (LCST), which is approximately 32°C. The COMSOL Multiphysics® software with Heat Transfer Module is used to ...

Simulating Light Propagation during I-PDT of Locally Advanced Head and Neck Cancer

E. Oakley [1], H. Arshad [1], G. Shafirstein [1],
[1] Roswell Park Cancer Institute, Buffalo, NY, USA

Interstitial photodynamic therapy (I-PDT) can be applied for the treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The complex anatomy of LA-HNSCC requires careful planning of the light delivery and fiber insertion. We have developed an image-based approach, using finite element analysis, to suggest the number and location of treatment fibers needed for I-PDT and to ...