Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Magnetostatic-Magnon Sensors for Microwave Microscopy of Biological Structures - new

E. Hollander[1], E. O. Kamenetskii[1], R. Shavit[1]
[1]Microwave Magnetic Laboratory, Department of Electrical and Computer Engineering, Ben Gurion University of the Negev, Beer Sheva, Israel

Microwave sensing and monitoring is very attractive for biological applications because of their sensitivity to water and dielectric contrast. Direct detection of biological structures in microwave frequencies and understanding of the molecular mechanisms of microwave effects is considered as a problem of a great importance. Nowadays, however, microwave technique for localized testing biological ...

Image Based Mesh Generation for Realistic Simulation of the Transcranial Current Stimulation

R. Said[1], R. Cotton[1], P. Young[1], A. Datta[2] , M. Elwassif[2], and M. Bikson[2]
[1]Simpleware Ltd, Exeter, UK
[2]Department of Biomedical Eng, The City College of New York, USA

Electrical stimulation of the brain involves the application of currents delivered through scalp electrodes to modulate brain activity, known as Transcranial Current Stimulation (TCS). A critical factor for TCS efficacy and safety is the “spatial focality” of induced neuronal modulation. Bikson and coauthors from the City College of New York have been investigating the impact of disc ...

Optimizing Performance of Equipment for Thermostimulation of Muscle Tissue using COMSOL Multiphysics

J. Kocbach[1], K. Folgerø[1], L. Mohn[2], O. Brix[3]
[1]Christian Michelsen Research, Bergen, Norway
[2]Luzmon Norway, Bergen, Norway
[3]Michelsen Medical, Bergen, Norway

The design challenge for thermostimulation equipment is to get a combination of high electric field strength and high temperature within the muscle tissue without causing pain or skin burns. In the present work, COMSOL Multiphysics is used to simulate the temperature distribution and electric field distribution within body tissue for varying body composition and varying design parameters of the ...

Human Torso Model for Heat Transfer Analysis

X. Xu[1], T. Patel[1], R.W. Hoyt[1]
[1]U.S. Army Institute of Environmental Medicine, Natick, MA, USA

A human torso model was created for heat transfer analysis. The torso was derived from the ‘Virtual Family’ whole-body voxel data from the ITIS Foundation (Zurich, Switzerland). Measurements were taken from the ITIS male along the axial plane at key anatomical landmarks and used to develop geometry in Solidworks. Individual components were created to represent the skin, fat, muscle, and bone ...

Electro Thermal Performance Prediction of Radio Frequency Ablation System for Efficient Cancer Treatment

C. Thiagarajan[1], V. Gnanasekar[2]
[1]ATOA Scientific Technologies Pvt Ltd, Whitefield, Bangalore, Karnataka, India.
[2]Perfint Healthcare Pvt. Ltd, T.Nagar, Chennai, India.

Cancer causes significant human deaths. Radiofrequency ablation is an encouraging procedure for cancer treatment. The objective is to demonstrate the multiphysics simulation methodology. This paper summarizes the problem , governing equations, methodology, assumptions, simulation results and discussion related to the thermal performance prediction of radio frequency ablation on a homogeneous ...

Can Oscillatory Convection Accelerate Signal Propagation in Simple Epithelium?

M. Nebyla[1], M. Pribyl[1]
[1]Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic

We introduce a mathematical model of signal transmission in simple epithelial layers. The mathematical model consists of reaction-transport equations for extracellular ligands, cellular receptors, ligand-receptor complexes and a ligand releasing protease. We consider diffusion and nonstationary convective transport of protein ligands in the extracellular space. The study was carried out using ...

A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry

Kristian Dreij[1], Qasim Ali Chaudhry[2], Bengt Jernström[1], Ralf Morgenstern[1], and Michael Hanke[2]
[1]Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
[2]School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden

A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. bioactivation ...

Cellular Scale Model of Stratum Corneum

R. Santoprete[1], B. Querleux[1]
[1]L'Oréal, Paris, France

To better quantify the impact of the morphological and mechanical properties of the main constituents of the stratum corneum (SC, the outermost layer of the skin) on its overall mechanical behavior, we developed a biomechanical model of the SC at a cellular scale, based on in vitro morphological and mechanical data. The sensitivity analysis quantified the relative impact of the mechanical and ...

Finite Element Analysis of Defibrillation Current Density in Pregnant Women

A. Jeremic[1], E. Khosrowshahli[1]
[1]McMaster University, Hamilton, ON, Canada

Although resuscitation during pregnancy is relatively uncommon and rarely causes death, they have a particularly large impact in terms of the mortality of the unborn child and long-term effects on families and society as whole. In this paper, we present a new 3D finite element model of a pregnant female torso which accounts for presence of amniotic liquid and calculate current density ...

Design and Optimization of Cholesterol Biosensor

N. M. Sundaram[1], M. Alagappan[1]
[1]PSG College of Technology Coimbatore, Tamil Nadu, India

Cholesterol is an essential lipid for human body. The desired total plasma cholesterol for an individual is less than 5.2 mM (200 mg/dL) and it poses a potential health threat when the level is greater than 6.2 mM (240 mg/dL) [1]. Excessive plasma cholesterol causes poor cardiovascular conditions. The experimental fabrication of nano structured biosensor with advanced materials is more expensive ...