See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Image-Based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-Pulmonary Applications

F.K. Hermans[1], R.M. Heethaar[1], R.T. Cotton[2], and A. Harkara[2]

[1]VU University Medical Center, Amsterdam, The Netherlands
[2]Simpleware Ltd., Exeter, United Kingdom

For medical diagnostic purposes there is an increasing need for non- (or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the ... Read More

Passive and Active Deformation Processes of 3D Fibre-Reinforced Caricatures of Cardiovascular Tissues

A. Di Carlo[1], P. Nardinocchi[2], T. Svaton[3], and L. Teresi[1]

[1]Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
[2]Dept. of Structural & Geotechnical Engineering, Università di Roma La Sapienza, Roma, Italy
[3]Dept. of Mathematics, University of West Bohemia, Pilsen, Czech Republic

In this paper, we present a mathematical model of contractile elastic solids meant to simulate various districts of the cardiovascular system, and based on the concepts of active deformation and embedded muscle fibres. Specifically, here we deal with the modeling of the gross mechanics ... Read More

Bayesian Estimation of Tumors in Breasts Using Microwave Imaging

A. Jeremic[1], E. Khosrowshahli[1]
[1]McMaster University, Hamilton, ON, Canada

Although mammography is extremely important diagnostic technique, it suffers from some limitations such as false negative and positive results, using ionizing radiation and patient’s discomfort. Microwave imaging has been recently proposed as an additional medical imaging technique ... Read More

Modelling the Response of Microdialysis Probes in Glucose Concentration Measurement

J.M. Gozálvez-Zafrilla[1], A. Santafé-Moros[1], J.L. Díez-Ruano[2], J. Bondia[2]
[1]Institute for Industrial, Radiophysical and Environmental Safety (ISIRYM) - Universitat Politècnica de Valencia, Valencia, Spain
[2]Instituto Universitario de Automática e Informática Industrial (AI2) - Universitat Politècnica de Valencia, Valencia, Spain

Microdialysis is a technique of continuous glucose monitoring in diabetic patients. In microdialysis, a saline serum is perfused into a microdialysis probe. Glucose pass from the plasmatic fluid through the porous membrane. The glucose concentration in the dialysate obtained is measured ... Read More

Simulation of Normal and Cancerous T-cell Membrane Electroporation new

O. Henao[1], V. Gómez[1], I. De la Pava[1], J. Sánchez[1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field [1][2]. The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs ... Read More

Updated Results of Singlet Oxygen Modeling Incorporating Local Vascular Diffusion for PDT new

R. Penjweini[1], M. M. Kim[1], T. C. Zhu[1]
[1]Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA

Introduction: Singlet oxygen (¹O₂) has a critical role in the cell-killing mechanism of photodynamic therapy (PDT). Therefore, in this study, the distance-dependent reacted ¹O₂ is numerically calculated using finite-element method (FEM). Herein, we use a model [Ref. 1] that has been ... Read More

Drop Simulation of Disposable Elastomeric Pump Using COMSOL Multiphysics® Software

R. Kapuganti [1], S. Anbazhagan[1],
[1] HCL Technologies, Chennai, India.

Drop test simulation is one of the important tool used for the impact behaviour study of electronic components. It identifies the flaws in design. The reliability and performance of electronic consoles after the drop is a major concern. Devices are expected to continue functioning after ... Read More

A Model to Simulate Laser Ablation in Tumor Using Dynamic Photothermal Coupling Interaction Model

Zhifang Li [1], Xiyang Zhang [1],
[1] College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou, China

Laser immunotherapy (LIT) was developed to treat late-stage, metastatic cancers through local laser irradiation and immunological stimulation. In ILIT, the photothermal effect induces immune responses by destroying and interrupting tumor cells through temperature elevation in target ... Read More

Optical Monitoring Method of Sessile Droplet Evaporation

V. Tishkova [1], R. Grossier [1], S. Veesler [1],
[1] Aix Marseille Univ, CNRS, Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Marseille, France

Nano and pico-litre sessile droplet are of large interest in many areas including pharmaceutical and biomedical applications. In particularly it can be used for drug delivery, protein testing or to control nucleation in confined environment. Industrial and research use of such methods ... Read More

Frequency and Electrode Separation Recommendations for EDA Measurements

S. Sridhar [1], T. J. Akl [1],
[1] Analog Devices Inc., Wilmington, MA, USA

Electrodermal Activity (EDA) is a measure of changes in the conductivity of the skin. It has have been found to be indicative of the individual’s autonomic nervous activity which is correlated to their stress and emotional state. These conductivity changes are tracked by injecting a ... Read More