M. Kaushik , S. Katti , V. Saradesai , P. Naragund , P. Vidhyashree , A. K. V. Nandi 
 B.V. Bhoomaraddi College of Engineering and Technology, Hubli, India
This article describes the design of MEMS based cantilever structure intended for determination of blood group and it is compared with manual method. Cantilever structure design has a sensing layer and when a blood sample comes in contact with this, results in coagulation. The surface tension in turn occurs due to chemical and biological reactions of antigen and antibodies resulting in ...
H. Kwon, R. Huancaya
Andrews University, Berrien Springs, MI, USA
Vein visualization systems such as the VeinViewer are vein-contrast enhancement devices that use an infrared camera to highlight blood or the underlying vasculature and project the image in real time onto the skin. Understanding the light propagation in a realistic skin model is critical, but only a few computational models have been developed to account for this particular system. We have ...
J. F. Hansen ,
 Thoratec Corporation, CA, USA
When an electronic device is worn for extended periods, possibly in direct contact with human skin, heat must be safely transferred away from the device, without exceeding standards and regulatory temperature limits on the skin and on the exposed surfaces of the device. Heat transfer is dominated by convective heat transfer to the surrounding air (possibly trapped air under clothing), and by ...
K. Cluff, L. Saeednia, H. Mehraein , R. Asmatulu
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been used as in-situ hydrogel formulations. These polymeric formulations can form gels at body temperature while ...
A. Dwivedi , G. Khanna ,
 NIT Hamirpur, Hamirpur, Himachal Pradesh, India
This work describes the design and optimization of three prototypes of microelectromechanical systems (MEMS) capacitive accelerometer-based middle ear microphone. The microphone is intended for middle ear hearing aids as well as future fully implantable cochlear prosthesis. The analysis is done using COMSOL Multiphysics®. The maximum applied acceleration was considered 1g. Human temporal bones ...
P. Nakielski, T. Kowalczyk, T.A. Kowalewski
Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, Poland
Comprehensive studies of drug transport in nanofibres based mats have been performed to predict drug release kinetics. The paper presents our approach to analyze the impact of fibers arrangement, one of the parameters varied in our parallel experimental studies. COMSOL Multiphysics® has been used to assess the impact of the various purposed arrangements of fibers within the mat. Drug release ...
K. Carlson , J. Arle , J. L. Shils , L. Mei ,
 Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA
 Rush Medical Center, Chicago, IL, USA
In 1901 Weiss proposed an equation predicting activation of nerve fibers by electrical stimulation, used in neuroscience and neuromodulation, which applies electric fields to modify nerve behavior in neurological disorders. Weiss’ equation is relative to geometry, electrode array, tissue conductivities, and waveform since it uses electrode amplitude. We replicated a leading calibrated nerve ...
M. Christian, S. Firebaugh, A. Smith
United States Naval Academy, Annapolis, MD, USA
This project utilizes the heat transfer module of the COMSOL Multiphysics environment to model the effects that an ohmic heating probe will have on neural tissue. The model quantifies the thermal impact of active components embedded on a neural micro probe by solving the Penne’s bioheat equation with an external MATLAB function to determine the heat generation along the length of the probe. The ...
Magnetic Heating of Iron Oxide Nanoparticles with Alternating Magnetic Field for Hyperthermia Applications
N. M. Sundaram, M. Sneha, R. S. Vishnu, M. Alagappan
PSG College of Technology Coimbatore, Tamil Nadu, India
The current therapies available to treat cancer patients are surgical operation and chemo therapy. The drawbacks are the side effects caused by these therapies. Hyperthermia is a treatment technique based on deactivation of cancer cells by raising the temperature in the range of 43 ºC and 48 ºC and has gained attention as an alternative therapy for cancer treatment. Iron oxide nanoparticles have ...
S. Biswas, S. Das, M. Mahadevappa
Advanced Technology Development Center, Indian Institute of Technology, Kharagpur
School of Medical Science and Technology, Indian Institute of Technology, Kharagpur
Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) are diseases causing blindness in a large number of people. In this type of degenerative disease, mostly the photoreceptors are damaged. Thus attempts have been made to electrically stimulate the surviving inner retinal neurons and retinal ganglion cells (RGC) in order to restore vision. In this paper, the electrode-tissue ...