Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Near-Field FEM Simulations: A Vital Tool for Studying Silver-Based Plasmonic Systems

R. Asapu [1], S. W. Verbruggen [2], N. Claes [3], S. Bals [3], S. Denys [1], S. Lenaerts [1],
[1] Department of Bioscience Engineering, DuEL Research Group, University of Antwerp, Antwerp, Belgium
[2] Department of Bioscience Engineering, DuEL Research Group, University of Antwerp, Antwerp, Belgium; Center for Surface Chemistry and Catalysis, KU Leuven, Leuven, Belgium
[3] Department of Physics, EMAT Research Group, University of Antwerp, Antwerp, Belgium

Silver nanoparticles are valuable in the field of plasmonics since silver has a higher field enhancement factor compared to other metals that possess plasmonic properties. The plasmonic properties of silver nanoparticles can be finely tuned to the incident light wavelength through their size, shape and dielectric environment, and they have long-term stability. In this work, an ultrathin polymer ...

Modeling of Hydrogel-Based Controlled Drug Delivery System for Breast Cancer Treatment - new

K. Cluff[1], L. Saeednia[2], H. Mehraein [1], R. Asmatulu[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA

Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been used as in-situ hydrogel formulations. These polymeric formulations can form gels at body temperature while ...

Modeling Light Propagation in Skin for Visualization of Subcutaneous Veins

H. Kwon[1], R. Huancaya[1]
[1]Andrews University, Berrien Springs, MI, USA

Vein visualization systems such as the VeinViewer are vein-contrast enhancement devices that use an infrared camera to highlight blood or the underlying vasculature and project the image in real time onto the skin. Understanding the light propagation in a realistic skin model is critical, but only a few computational models have been developed to account for this particular system. We have ...

Pushability Model of a Microcatheter for Intravascular Procedures

M. Miliani[1], F. Piccagli[1]
[1]Medtronic Invatec S.p.A., Roncadelle, BS, Italy

During peripheral intravascular interventions one of the main issues is the correct deployment of the guidewire (GW) to the anatomical site which has to be treated, often supported by a microcatheter. There is a trade-off between the microcatheter flexibility and its push-ability to be able to reach the anatomical site. The catheter design has been defined with 2 transition zones. A parametric ...

Magnetic Heating of Iron Oxide Nanoparticles with Alternating Magnetic Field for Hyperthermia Applications

N. M. Sundaram[1], M. Sneha[1], R. S. Vishnu[1], M. Alagappan[1]
[1]PSG College of Technology Coimbatore, Tamil Nadu, India

The current therapies available to treat cancer patients are surgical operation and chemo therapy. The drawbacks are the side effects caused by these therapies. Hyperthermia is a treatment technique based on deactivation of cancer cells by raising the temperature in the range of 43 ºC and 48 ºC and has gained attention as an alternative therapy for cancer treatment. Iron oxide nanoparticles have ...

Simulating Spiking Neurons Using a Simple Mathematical Model

S. Kirigeeganage [1], J. Naber [1], D. Jackson [1], R. Keynton [1], T. Roussel [1],
[1] University of Louisville, Louisville, KY, USA

This paper utilizes COMSOL Multiphysics® software and the Application Builder to simulate neurological responses in nerve axons due to external electrical stimuli. The AC/DC Module of the COMSOL® software is first used to solve the Maxwell's equations. Then the results from the Maxwell's equations are used to drive a second model constructed using global equations using the Global ODE and DAE ...

Modeling Drug Release from Materials Based on Electrospun Nanofibers

P. Nakielski[1], T. Kowalczyk[1], T.A. Kowalewski[1]
[1]Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, Poland

Comprehensive studies of drug transport in nanofibres based mats have been performed to predict drug release kinetics. The paper presents our approach to analyze the impact of fibers arrangement, one of the parameters varied in our parallel experimental studies. COMSOL Multiphysics® has been used to assess the impact of the various purposed arrangements of fibers within the mat. Drug release ...

Simulation of Transdermal Toxin Expulsion via Adsorptive Dermal Patch using COMSOL Multiphysics®

H. Kwon[1], M. Hess II[1], R. M. Polski
[1]Andrews University, Berrien Springs, MI, USA

Mathematical skin models play an important role in fields such as transdermal drug delivery and assessment of dermal exposure to industrial chemicals. Extensive research has been conducted on modeling skin for transdermal drug delivery; however, little effort has been made to view the skin as a permeable layer to expel waste chemicals or toxins from the body. In this work, we focused on topical ...

A Non-Newtonian Model for Blood Flow behind a Flow Diverting Stent

G. Mach [1], C. Sherif [2], U. Windberger [3], A. Gruber [3],
[1] Vienna University of Technology, Cerebrovascular Research Group Vienna, Vienna, Austria
[2] Hospital Rudolfstiftung, Cerebrovascular Research Group Vienna, Vienna, Austria
[3] Medical University Vienna, Cerebrovascular Research Group Vienna, Vienna, Austria

Usually, when calculating the blood flow in cerebral arteries and intracranial aneurysms, blood is modeled as a Newtonian fluid, neglecting its shear-thinning behavior. Since flow diverting devices slow down the blood flow in the aneurysm sack, the accuracy of this assumption had to be reviewed. A Carreau Yasuda model is introduced as a non-Newtonian model for blood viscosity. CFD simulations of ...

COMSOL Thermal Model for a Heated Neural Micro-Probe

M. Christian[1], S. Firebaugh[1], A. Smith[1]
[1]United States Naval Academy, Annapolis, MD, USA

This project utilizes the heat transfer module of the COMSOL Multiphysics environment to model the effects that an ohmic heating probe will have on neural tissue. The model quantifies the thermal impact of active components embedded on a neural micro probe by solving the Penne’s bioheat equation with an external MATLAB function to determine the heat generation along the length of the probe. The ...