E. Isaza, E. Salazar, L. Florez
Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia
The consequences of hip fracture and femoral fracture are widely known. The mechanical strength of the femur varies in every person, but it is possible to predict the mechanical resistance with parameters like density, dimensions and mineral content. This paper uses different models and empirical studies to determine the mechanical properties of the human femur, developing isotropic and ...
K. Cluff, L. Saeednia, H. Mehraein , R. Asmatulu
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been used as in-situ hydrogel formulations. These polymeric formulations can form gels at body temperature while ...
E. Lacatus, M. A. Sopronyi, G. C. Alecu, A. Tudor
Polytechnic University of Bucharest, Bucharest, Romania
INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania
For biocompatible prosthetics, from dental implants up to bone parts, manufacturers have to find the best way to correlate process parameters and the material properties as to meet the unique needs of individuals. Additive manufacturing techniques aim at creating complex biocompatible structures able to overcome the present shortfalls of the metal and metal alloys implants related to ...
K. Jindal , V. Grover , B. Nayak ,
 Birla Institute of Technology and Science - Pilani, Ghaziabad, Uttar Pradesh, India
Microarrays are extensively used in modern biology as tools of multiplexed, high throughput analysis to study thousands of genes and their expression inside cells at once . The basic principle of a microarray is quantitative detection of fluorophore tagged DNA. Use of this method results in microarray experiments being expensive and complex due to fragile and costly fluorophores and ...
R. L. Spilker
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, New York, USA
In this presentation, we study the modeling of physiology and muscoskeletal biomechanics using COMSOL. The outline for the presentation is in particular: Why is COMSOL particularly powerful for modeling physiology? Modeling soft tissues like cartilage Optimization to determine soft tissue properties Modeling of moving loads in the TMJ Robust 3D models from imaging data Model of primary ...
H. Kwon, M. Hess II, R. M. Polski
Andrews University, Berrien Springs, MI, USA
Mathematical skin models play an important role in fields such as transdermal drug delivery and assessment of dermal exposure to industrial chemicals. Extensive research has been conducted on modeling skin for transdermal drug delivery; however, little effort has been made to view the skin as a permeable layer to expel waste chemicals or toxins from the body. In this work, we focused on topical ...
H. Ghosh , C. Roychaudhuri ,
 Indian Institute of Engineering Science and Technology (IIEST), Shibpur, Howrah, West Bengal, India
This paper explores surface charge modulated ionic conductance of closed solid-state nanopores for explaining significant nonlinear length dependent variation in ionic current in such nanopore biosensors with a view to design improved sensors without increasing fabrication cost for biomolecule detection. Although extensive work has been done in modeling open pore conductance, closed nanopores ...
A. R. Hambarde , R. M. Patrikar ,
 Visvesvaraya National Institute of Technology, Nagpur, Maharashtra, India
Microelectromechanical coupled resonating arrays are being used for detecting biological and chemical analytes through mass sensing. Such arrays of perfectly identical resonators can be considered as periodic, ordered, non-localized systems. The change in the eigen parameters of the system upon mass or stiffness perturbation is a measure of the amount of perturbation. An attempt has been made in ...
Comparing Isotropic and Anisotropic Brain Conductivity Modeling: Planning Optimal Depth-Electrode Placement in White Matter for Direct Stimulation Therapy in an Epileptic Circuit
L. C. Zaragoza, B. Hondorp, M. A. Rossi
ITESM, Monterrey, Mexico
Rush Medical College, Chicago, IL, USA
Rush University Medical Center, Chicago, IL, USA
The goal of our work was to calculate a patient-specific brain conductivity map for predicting the extent to which direct stimulation therapy can strategically propagate through pathological white matter. Our laboratory developed isotropic and anisotropic human brain finite element method (FEM) models derived from SPGR magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI), ...
Magnetic Heating of Iron Oxide Nanoparticles with Alternating Magnetic Field for Hyperthermia Applications
N. M. Sundaram, M. Sneha, R. S. Vishnu, M. Alagappan
PSG College of Technology Coimbatore, Tamil Nadu, India
The current therapies available to treat cancer patients are surgical operation and chemo therapy. The drawbacks are the side effects caused by these therapies. Hyperthermia is a treatment technique based on deactivation of cancer cells by raising the temperature in the range of 43 ºC and 48 ºC and has gained attention as an alternative therapy for cancer treatment. Iron oxide nanoparticles have ...