Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Analyzing Drug Delivery and Osteoblast Growth on a Porous Scaffold in a Perfusion Bioreactor

A. Sun, and S. Murray
Dept. of Biomedical Engineering
UCLA, Los Angeles, CA

Implantable Collagen sponges are used in Spinal Surgery as Drug Delivery Scaffolds. An optimal concentration of growth factor that strikes a balance between bone growth and adverse diffusion effects is difficult to find. The porous sponge also serves as a scaffold for Osteoblast growth, and fluid shear has been shown to mediate biological effects on that cell type. We use COMSOL Multiphysics ...

Bone Remodeling Following Total Hip Replacement: Short Stem Versus Long Stem Implants

M.S. Yeoman[1], A. Cizinauskas[1], C. Lowry[2], G. Vincent[3], S. Collins[3], D. Simpson[3]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]Corin Group, Cirencester, United Kingdom
[3]Imoprhics, Manchester, United Kingdom

Bone resorption around hip stems, in particular periprosthetic bone loss, is a common observation post-operatively. A number of factors influence the amount of bone loss over time and the mechanical environment following total hip replacement (THR) is important. Conventional long stem prostheses have been shown to transfer loads distally, resulting in bone loss of the proximal femur. More ...

Piezoelectric Transducers and Ultrasound Imaging: Impact of Materials Properties and Multiphysics Aided Design

Marco Cati graduated cum laude and encomium citation in electronic engineering in 2001 from the University of Florence, where in 2005 he also received a Ph. D. degree in electronic engineering. In 2005 he joined the Research & Development Department of Esaote where he is currently in charge of electromagnetic compatibility (EMC) design and testing activities on ultrasound and magnetic resonance ...

Drug Distribution in the Human Eye

L. Murtomäki[1], T. Kainuvaara[1]
[1]University of Helsinki, Helsinki, Finland

Drug therapy of the posterior segment of an eye is very challenging due to the difficult accessibility. Modern drugs often are large molecules, such as peptides, antibodies or oligonucleotides which are administrated, e.g. by intravitreous injections which requires clinical conditions. Computer modeling can be helpful in designing new and less invasive routes of drug administration. COMSOL is ...

The Friction Coefficient of Fractal Aggregates in the Continuum and the Transition Regimes

A. Melas[1][3], A.G. Konstandopoulos[1], L. Isella[2], Y. Drossinos[1]
[1]Department of Chemical Engineering, Aristotle University, Thessaloniki, Greece
[2]European Commission, DG Energy, Luxemburg
[3]European Commission, Joint Research Centre, Ispra, Italy

Aerosol and colloid aggregates are complex fractal-like structures composed of primary spheres. The drag force exerted on a fractal-like object is usually determined by solving numerically the Stokes equation. In this study we calculate it by relating it to a molecule-aggregate collision rate. We create the fractal aggregates with a cluster-cluster aggregation algorithm using the software ...

Coupling Forced Convection in Air Gaps with Heat and Moisture Transfer inside Constructions

M. Bianchi Janetti[1], F. Ochs[1]
[1]University of Innsbruck, Innsbruck, Austria

Introduction: The simulation of coupled heat and moisture transfer in constructions is becoming even more important in the last years. COMSOL Multiphysics represents a powerful tool for this kind of simulations as shown in [1,2,3], although applications in this area are still rare. For the realistic prediction of the heat and moisture distribution in building elements exposed to external ...

Lowering of the Interstitial Fluid Pressure as a Result of Tissue Compliance Changes during High Intensity Focused Ultrasound Exposure: Insights from a Numerical Model

E. Sassaroli[1], B. O'Neill [1]
[1]The Methodist Hospital Research Institute, Houston, TX, USA

Interstitial fluid pressure (IFP) is elevated in tumors. Owing to this elevated IFP, the interstitial fluid velocity (IFV) is negligible throughout the tumor but significant near the tumor margin. Any therapeutic strategy that can lower IFP will improve drug convection within the tumor and decrease convection of drugs from the tumor margin. High intensity focused ultrasound (HIFU) has been shown ...

Thermo-Fluid Dynamics of Flue Gas in Heat Accumulation Stoves: Study Cases

D. Rossi[1], P. Scotton[1]
[1]University of Padova, Department of Geosciences, Padova, Italy

The research aims to clarify some aspects of the thermo-fluid dynamics of woody biomass flue gas, within the twisted conduit inside the heat accumulation stoves, and exposes also some analysis about the heat transport and heat exchange processes. The high temperature flue gas flows in the conduit, releasing heat to the refractory. The heat stored in the refractory is then released to the ...

Energetics of Half-Quantum Vortices

K. Roberts[1]
[1]University of Illinois at Urbana-Champaign, Urbana, IL, USA

Magnetic cantilever measurements have detected half-flux states in mesoscopic rings of the layered material Sr2RuO4, adding evidence that superconducting Sr2RuO4 may be described by a p-wave order parameter. A proposal accounting for this behavior has been presented in which the polarization axis of the condensates lies entirely in the plane. In a half-flux state there is a non-zero ...

Multiphysics Simulations in the Ultrasonic Industry

P.A. Colombo[1]
[1]DepQuest, Dalmine, Italy

This work focuses on the application of multiphysics finite element simulations in the manufacturing and application of high power ultrasonic machines. Industries providing big power ultrasonic solutions as in cleaning, welding, sonochemistry and cutting fields, already apply the finite element simulation approach, in the structural mechanics flavor, in the design and optimization of ultrasonic ...

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