COMSOL Multiphysics® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology
F. Rossi and R. Pini
Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy
In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation mode and diffusion approximation were used to design a theoretical model of blue LED light interaction with an ...
R. Dufour , C. Wu, F. Bendriaa, V. Thomy, and V. Senez
BioMEMS Group, IEMN, University of Lille Nord de France, Villeneuve d’Ascq, France
This paper presents an Analog to Digital Microfluidic Converter (ADMC) using passive valves and enabling the conversion of a continuous liquid flow into droplets for Electro-Wetting On Dielectric (EWOD) actuation. Valves calibration, geometry characteristics and losses reduction have been optimized using microfluidic application mode of COMSOL Multiphysics®.
D. Song, R. Gupta, and Chhabra
West Virginia University, Morgantown, West Virginia, USA
Indian Institute of Technology, Kanpur, India
Heat transfer from a sphere having a uniform temperature and falling axially in a cylindrical tube filled with an incompressible power-law liquid is numerically investigated. The governing equations for simultaneous flow around a confined sphere and heat transfer to power-law fluids were solved numerically using COMSOL Multiphysics. It was found that the wall effects on the mean Nusselt number ...
M. Williams, J. Zito, J. Agashe, A. Sopeju, and D. Arnold
University of Florida, Gainesville, USA
This paper describes the design of a normally closed, electrodynamic microvalve. Magnetic forces between a permanent magnet in the valve cover and a soft magnet in the valve seat hold the valve closed. The combination of electrodynamic actuation and a mechanical restoring spring are used to open the valve. A device model and a design optimization strategy using COMSOL ...
J. Torres, and D. Montane
Centre Huile Lourde Ouvert et Experimental (CHLOE), University of Pau, France
Department of Chemical Engineering, Virgili University, Tarragona, Spain
Steam Reforming of Ethanol using a Catalytic Wall Reactor (CWR) was successfully studied using COMSOL Multiphysics. A mathematical model was used to describe the reactor performance in terms of the main variables and dimensionless groups. Simulations showed that at specified conditions CWR maintains a thermal performance adequate for evaluating catalysts under a uniform temperature profile. CWR ...
E. Zanchini, and T. Terlizzese
Dipartimento di Ingegneria Energetica, Nucleare e del Controllo Ambientale, Università di Bologna, Bologna, Italy
The results of two thermal response tests recently performed on two vertical borehole heat exchangers (BHEs) are presented. The BHEs have the same cross section and a depth of 100 m and 120 m respectively. The evaluation of the thermal properties of the ground and grout are performed by a finite-element simulation method, developed through the software package COMSOL Multiphysics 3.4.
O. Nicotra, and A. La Magna
CNR-IMM Sezione di Catania, Catania, Italy
One of the major applications for dielectrophoresis is the selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particle effects due to high concentrations of biological material around electrodes can cause a rapid decrease of trapping efficiency in dielectrophoretic devices. In this contribution we present a new approach based on a drift-diffusion dynamics to study ...
G. Cammarata, and G. Petrone
Department of Industrial and Mechanical Engineering, University of Catania, Catania, Italy
In this study fluid-dynamical and thermal performance of active chilled beams is investigated by 2D and 3D modelling in COMSOL Multiphysics. Three different typologies of those air conditioning systems are considered. Results, obtained for typical range of variation of operational conditions, are principally produced as temperature and velocity distributions. Special attention is paid to the ...
Department of Chemical Engineering, M.I.T., Cambridge, MA, USA
Magnetic fluids containing nano or submicron magnetic particles and their application in food, biological and pharmaceutical systems have recently attracted increasing attention. Magnetic particles can be collected efficiently in magnetizable matrices (e.g. iron wires) in high gradient magnetic separation (HGMS) process. In this work, the dynamic buildup growth process is treated as a moving ...
J. E. Toney
Pennsylvania State University Electro-Optics Center, Freeport, Pennsylvania, USA
We demonstrate the use of Comsol Multiphysics with Matlab to model signal generation in wide-bandgap semiconductor radiation detectors. A quasi-hemispherical detector design is compared with a simple, planar detector. Results show that the quasi-hemispherical design can simply and effectively compensate for the poor hole transport of most compound semiconductor materials.