Comparison of Finite Element and Monte Carlo Simulations for Inhomogeneous Advanced Breast Cancer Imaging
Y. Xu, and Q. Zhu
University of Connecticut, Storrs, CT, USA
Three-dimensional FEM method provided by COMSOL is used to model an inhomogeneous advanced breast tumor of different optical properties for outer layer and inner core in a semi-infinite medium. The running time of FEM by COMSOL for one source and 14 detectors is 17.658s and which of Monte Carlo (MC) is 91017s, 5154 times longer. The absorption distribution is reconstructed by born approximation. ...
J. Anza, and M. Esteves
Department of applied mathematics, University of the Basque Country, Bilbao, Spain
University of the Basque Country, Bilbao, Spain
This work deals with the computer simulation of the blood flow, the arterial wall deformation and their 3D bidirectional interaction, including initial stresses and root displacements. The flow is laminar and steady with flexible walls modeled with a hyperelastic Demiray material model. Poiseuille formula is used to check the bidirectional interaction. 2D axisymmetric and full 3D models have ...
Optimizing Performance of Equipment for Thermostimulation of Muscle Tissue using COMSOL Multiphysics
J. Kocbach, K. Folgerø, L. Mohn, O. Brix
Christian Michelsen Research, Bergen, Norway
Luzmon Norway, Bergen, Norway
Michelsen Medical, Bergen, Norway
The design challenge for thermostimulation equipment is to get a combination of high electric field strength and high temperature within the muscle tissue without causing pain or skin burns. In the present work, COMSOL Multiphysics is used to simulate the temperature distribution and electric field distribution within body tissue for varying body composition and varying design parameters of the ...
A. Jeremic, E. Khosrowshahli
McMaster University, Hamilton, ON, Canada
Although resuscitation during pregnancy is relatively uncommon and rarely causes death, they have a particularly large impact in terms of the mortality of the unborn child and long-term effects on families and society as whole. In this paper, we present a new 3D finite element model of a pregnant female torso which accounts for presence of amniotic liquid and calculate current density ...
T. Maguire [1,2], M. Davis , I. Marrero-Berrios , C. Zhu , C. Gaughan , J. Weinberg , D. Manchikalapati , J. SchianodiCola , R. S. Schloss , J. Yarmush , M. Yarmush ,
 Rutgers University, New Brunswick, NJ, USA
 BeauRidge Pharmaceuticals, New York, NY, USA
 Department of Anesthesiology, New York Methodist Hospital, Brooklyn, NY, USA
Introduction: While general anesthetics control pain via consciousness regulation, local anesthetics (LAs) act by decreasing sensation in the area of administration by blocking nerve transmission to pain centers. Perioperative intra-articular administration of LAs is a commonly employed procedure in orthopedic procedures to minimize patient surgical and post-surgical pain. LAs are also co ...
A. Eed Olamat, U. Hofmann, B. Pohl, and N. Nkemasong
University of Lübeck, Institute for Signal Processing, Lübeck, Germany
In order to investigate the implantation of microprobes into brain tissue, we developed a finite-element and a physical model to replace real biological tissue for mechanical testing. Penetrating forces of a tungsten indenter into a layered structure was investigated with different indentation speeds. Numerical and physical model are in good correspondence to each other and reproduce measured ...
Modeling of Retinal Electrical Stimulation Using a Micro Electrode Array Coupled with the Gouy-Chapman Electrical Double Layer Model to Investigate Stimulation Efficiency
F. Dupont, R. Scapolan, C. Condemine, J.F. Bêche, M. Belleville, and P. Pham
CEA, LETI, Minatec, Grenoble, France
The electrical stimulation for retinal implant has known significant improvements in the last decades with many implantations and experimentations. The ability to create better controlled and adapted signals to increase the efficiency in stimulation is a major objective. The aim of this study is to develop a numerical platform based on COMSOL Multiphysics to simulate different waveforms. The ...
A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry
Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernström, Ralf Morgenstern, and Michael Hanke
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. bioactivation ...
D. Iber, J. Vollmer, D. Menshykau
Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland
Most models of biological pattern formation are simulated on continuous domains even though cells are discrete objects that provide internal boundaries to the diffusion of regulatory components. In our previous papers on simulating organogenesis in COMSOL Multiphysics® (Germann et al COMSOL Multiphysics® Conf Procedings 2011; Menshykau and Iber, COMSOL Multiphysics® Conf Proceedings 2012) we ...
Computational Modeling of the Electrohydrodynamics Influencing Trace Mercury Adsorption within Electric Utility Electrostatic Precipitators
University of Michigan, Ann Arbor, MI, USA
Anthropogenic mercury (Hg) emissions increase the risk of neurological and neonatal health effects in humans through fish consumption. There are several technological approaches to controlling mercury emissions from coal combustion, including the injection of a powdered mercury sorbent into the flue gas upstream of the particulate control device (PCD). As most PCDs are electrostatic ...