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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Bioscience and Bioengineering

Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport

S. Conrad[1,2], P. Chittiboina[3], and B. Guthikonda[3]

[1]Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
[2]Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
[3]Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA

Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that reduce blood flow to the brain. Part of the approach to management of vasospasm is to improve flow through the stenotic areas by reducing by decreasing blood viscosity and enhancing ... Read More

Simulating Microbubble Flows Using COMSOL Multiphysics

X. Chen[1], and S. Ghadiali[1,2]

[1]Mechanical Engineering and Mechanics, Lehigh University, Bethlehem, PA, USA
[2]Bio Engineering program, Lehigh University, Bethlehem, PA, USA

Acute respiratory distress syndrome (ARDS) is a severe lung disease caused by a variety of direct and indirect insults. The main treatment for ARDS is mechanical ventilation. The ventilation of fluid filled lungs involves the propagation of microbubbles over a layer of epithelial cells. ... Read More

Modeling of Respiratory Lung Motion as a Contact Problem of Elasticity Theory

R. Werner, J. Ehrhardt, and H. Handels
University Medical Center Hamburg-Eppendorf, Germany

Breathing motion is a major problem in radiotherapy of lung tumors. The development of techniques to adequately account for respiratory motion requires detailed knowledge about breathing dynamics. Thus, computer aided modeling of respiratory motion gains in importance. In this paper we ... Read More

Coupled Fluid-Structural Analysis of Heart Mitral Valve

A. Avanzini, and G. Donzella
Department of Mechanical and Industrial Engineering, University of Brescia, Brescia, Italy

The mitral valve apparatus is a complex and refined mechanism located between the left atrium and the left ventricle of the heart which can manifest various kinds of pathologies. In order to support identification of potentially critical conditions resulting from some typical ... Read More

Virtual Thermal Ablation in the Head and Neck using COMSOL Multiphysics

U. Topaloglu[1], Y. Yan[2], P. Novak[2], P. Spring[3], J. Suen[3], and G. Shafirstein[3]
[1] Department of Information Technology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[2]Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[3]Department of Otolaryngology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

Thermal ablation in the head and neck requires accurate thermal dose delivery to target tissue while protecting the structure and function of nearby tissue and organs. In this study, we present a method that allows importing Computed Tomography (CT) scans to COMSOL, in order to model ... Read More

Simulating Hodgkin-Huxley-like Excitation using Comsol Multiphysics

J. Martinek[1,2], Stickler[2] , Reichel[1], and Rattay[2]
[1]Department of Biomedical Engineering and Environmental Management, University of Applied Sciences Technikum Wien, Vienna, Austria
[2]Institute for Analysis and Scientific Computing, Vienna University of Technology, Austria

Most simulations concerning electrical activation of human muscles are based on the modeling approach of Hodgkin and Huxley. Calculating the response of a muscle or nerve fiber membrane to an applied electrical field, needs to consider the “macroscopic”, extracellular potential ... Read More

Modeling of snRNP Motion in the Nucleoplasm

M. Blaziková[1], J. Malínský[2], D. Stanek[3], and P. Herman[1]
[1]Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
[2]Institute of Experimental Medicine, Prague, Czech Republic
[3]Institute of Molecular Genetics, Prague, Czech Republic

Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the ... Read More

Heat and Mass Transfer in Convective Drying Processes

C. Gavrila[1], A. Ghiaus[1], and I. Gruia[2]
[1]Technical University of Civil Engineering Bucharest, Faculty of Building Services, Bucharest, Romania
[2]University of Bucharest, Faculty of Physics, Bucharest, Romania

A dynamic mathematical model, based on physical and transport properties and mass and energy balances, was developed for the simulation of unsteady convective drying of agricultural products (fruits and vegetables) in static bed conditions. The model utilizes water sorption isotherm ... Read More

Validation of Measurement Strategies and Anisotropic Models Used in Electrical Reconstructions

R. Sadleir
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA

We are developing approximations of electrically anisotropic materials for use in novel imaging methods. Our modeling work in COMSOL comprises comparisons of anisotropic and layered models in terms of electrical conductivities measured using different strategies. We tested solution ... Read More

Image Based-Mesh Generation for Realistic Simulation of theTranscranial Current Stimulation

R. Said[1], R. Cotton[1], P. Young[1], A. Datta[2], M. Elwassif[2] , and M. Bikson[2]
[1] Simpleware Ltd, Exeter, Devon, UK
[2] Department of Biomedical Eng., The City College of New York, New York, NY, USA

This paper will discuss the comprehensive solution adopted for converting the 3D digital/medical images directly into the computational model. The workflow using Simpleware Software – ScanIP and + ScanFE – will be illustrated including the option for directly exporting fully compatible ... Read More

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