Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Near-Wall Dynamics of Microbubbles in an Acoustical Trap - new

L. Wright[1], G. Memoli[1], P. Jones[2], E. Stride[3]
[1]National Physical Laboratory, Teddington, UK
[2]University College London, London, UK
[3]University of Oxford, Oxford, UK

Understanding the interactions between microbubbles and surfaces is key to the successful deployment of microbubbles in a range of applications. Two important examples are their use as a drug delivery mechanism, and their potential use of acoustically-driven bubbles as microscale sensors. Drug delivery with bubbles involves sonication at high frequency close to a boundary, and sensing with ...

DNA Interactions in Crowded Nanopores - new

K. Misiunas[1], N. Laohakunakorn[1], S. Ghosal[2], O. Otto[1], U. F. Keyser[1]
[1]University of Cambridge, Cambridge, UK
[2]Northwestern University, Evanston, IL, USA

The motion of DNA in crowded environments is a common theme in physics and biology. Examples include gel electrophoresis and the self-interaction of DNA within cells and viral capsids. Here we study the interaction of multiple DNA molecules within a nanopore by tethering the DNA to a bead held in a laser optical trap to produce a "molecular tug-of-war". We measure this tether force as a function ...

Modelagem Computacional de Difusores para Microbombas

A. G. S. Barreto Neto [1], A. M. N. Lima [2], C. S. Moreira [1],
[1] Instituto Federal de Ciência e Tecnologia - IFPB, João Pessoa, PB, Brasil
[2] Universidade Federal de Campina Grande - UFCG, Campina Grande, PB, Brasil

Este trabalho trata do dimensionamento da estrutura bocal/difusor utilizando a simulação computacional com fronteira móvel. Esse tipo de simulação contempla toda estrutura da bomba, isto é, câmara de bombeamento, difusor e área de dispersão de fluxo, de modo a contabilizar o refluxo em função da estrutura, possibilitando um projeto mais realísticos da estrutura.

Study of Fluid and Mass Adsorption Model in the QCM-D Sensor for Characterization of Biomolecular Interaction

H.J. Kwon[1], C.K. Bradfield[1], B.T. Dodge[1], and G.S. Agoki[1]
[1]Department of Engineering and Computer Science, Andrews University, Berrien Springs, Michigan, USA

Increasing attention has been paid to application of the quartz crystal microbalance with dissipation (QCM-D) sensor for monitoring biomolecular interactions. This paper focuses on a practical application of protein-protein binding affinity measurement at low concentrations and minimal sample sizes (50-200 μl of 20-200 nM), which results in low signal measurement. A model simulating fluid ...

Dynamic Simulation of Electrochemical Etching of Silicon with COMSOL

A. Ivanov[1], U. Mescheder[1]
[1]Furtwangen University, Furtwangen, Germany

In the presented work the dynamic simulation of a silicon anodization process is performed. Two mechanisms of etch form development (diffusion in electrolyte, current flow) are considered and simulated. Influence of electrolyte conductivity and radius of the opening in the masking layer is discussed.

Multiphysics FEM Simulations Approach for Development of a MEMS Heat Generator

G. S. Masi[1], S. V. De Guido[1], G. Montagna[2], C. Martucci[2], P. M. Congedo[1], L. Vasanelli [1], M. G. Manera[2], R. Rella[2]
[1]Department of Innovation Engineering, University of Salento, Lecce, Italy
[2]CNR-IMM, Lecce, Italy

Introduction: Accurate fluid temperature control in microfluidic channels is a requirement for many lab-on-chip and micro-reactors.Thin films resistive metal heaters have proven to be the best choice for localizing heating applications with integrated microfluidic systems. A thin platinum layer has been chosen as the metal used to realize the meander because of its positive and linear ...

3D-Modeling of Magnetophoretic Separation of Superparamagnetic Dispersions Using COMSOL Multiphysics® Particle Tracing Module

D. Kleinehanding[1], L. Teich[1], C. Schröder[1]
[1]Department of Engineering Sciences and Mathematics, Computational Materials Science & Engineering (CMSE), University of Applied Sciences Bielefeld, Bielefeld, Germany

Magnetophoresis is a process of great interest for novel applications based on magnetic nanoparticles and colloids. Environmental applications like wastewater treatments and pollutant removal, biomedical applications like protein isolation, drug delivery, magnetic hyperthermia for cancer treatment, and magnetic-particle imaging are just a few of the numerous technological areas which exploit the ...

Positioning System for Particles in Microfluidic Structures

D. Kappe[1], A. Hütten[1]
[1]University of Bielefeld, Bielefeld, Germany

The possibility to detect and probe molecules in microfluidic devices gives rise to interesting applications. There are different approaches how to detect and probe particles, but a common step, for most methods, is to place the particles on a sensor. This can be done by applying external field gradients, or in this case by utilizing gravitational and hydrodynamic effects. Therefore, the sensor ...

Optimizing the Design of Polymer based Unimorph Actuator using COMSOL Multiphysics

V. Tiwari[1], R. Sharma[1], G. Srivastava[1], R. Dwivedi[1]
[1]Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Cantilever beam-type transducers have been in great demand and explored widely in the recent years, typically in thin film form because of their sensor and actuator applications. The piezoelectric cantilever is the most preferred structure employed in technological applications. Depending on the required flexural motion and sensitivities, these piezoelectric cantilevers can be used in unimorph, ...

COMSOL Multiphysics for the Designs and Applications on Biomicrofluidic Chips

I-Fang Cheng[1]
[1]National Nano Device Laboratories (NDL), National Applied Research Laboratories, Taipei, Taiwan

Some types of rare pathogens can be detected and identified in human blood through a low-cost and label-free method. The On-Chip SESR identification process has a fast detection time (about 5 minutes) and a low detection limit. Discrimination of a species is done by sorting red blood cells from bacteria. Simulations of dielectrophoretic (DEP) force, dual layer electrodes, and dynamic separation ...