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difussion and an immobilized enzyme

Posted Feb 3, 2011, 2:10 p.m. EST Chemical Reaction Engineering Version 4.1 0 Replies

Bradley Collier
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I am trying to develop a model of a reaction chamber that incorporates flow around a sensing gel. In order to do this I would like to immobilize an "enzyme" or species inside of the gel in the middle of the chamber. However, when I set the diffusion constant to zero inside of the gel, I am having trouble getting the solution to converge. I know that COMSOL can I have difficulties when using variables with vastly different values. I have heard about using logarithmic transform on the concentration fields, but I was not sure if this would work for the diffusion constants. I have tried changing my mesh and different properties of the solver, but I have yet to figure out a way to make the solution converge. I have attached my current file. Any help provided would be greatly appreciated. Thanks.
0 Replies Last Post Feb 3, 2011, 2:10 p.m. EST
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